CDE Detailed Report

Disease: content
Sub-Domain: Other Non-Motor
CRF: welcome

Displaying 1 - 50 of 100
CDE ID CDE Name Variable Name Definition Short Description Additional Notes (Question Text) Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guideline) Sub Domain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C10118 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - forget event severity score NMSSFrgetEvntSevScore The severity of the participant/subject forgetting things that he/she has been told a short time ago or events that happened in the last few days as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject forgetting things that he/she has been told a short time ago or events that happened in the last few days as part of the Non-Motor Symptom assessment scale for Parkinson's Disease. Does the patient forget things that he she has been told a short time ago or events that happened in the last few days? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10150 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - sex problem frequency severity value NMSSSexProbFreqSevVal The value of the frequency multiplied by severity for the participant/subject having problems having sex as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject having problems having sex as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have problems having sex? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10086 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - lost interest surrounding severity score NMSSLostIntrstSurrndSevScore The severity of the participant/subject losing interest in his/her surroundings as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject losing interest in his/her surroundings as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Has the patient lost interest in his her surroundings 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10129 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - difficulty swallow frequency NMSSDfcltySwllwFreq The frequency of the participant/subject having difficulty swallowing as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject having difficulty swallowing as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have difficulty swallowing? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10161 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - excess sweat severity score NMSSExcsSweatSevScore The severity of the participant/subject experiencing excessive sweating (not related to hot weather) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject experiencing excessive sweating (not related to hot weather) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient experience excessive sweating not related to hot weather? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10097 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - feel sad frequency severity value NMSSFeelSadFreqSevVal The value of the frequency multiplied by severity for the participant/subject being sad or depressed or has reported such feelings as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject being sad or depressed or has reported such feelings as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient seem sad or depressed or has he she reported such feelings? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10108 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - belief not true severity score NMSSBelfNotTrueSevScore The severity of the participant/subject having beliefs that you know are not true. For example, about being harmed, being robbed or being unfaithful as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject having beliefs that you know are not true. For example, about being harmed, being robbed or being unfaithful as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have beliefs that you know are not true? For example about being harmed being robbed or being unfaithful? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10140 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - void frequency severity value NMSSVoidFreqSevVal The value of the frequency multiplied by severity for the participant/subject having to void within 2 hours of last voiding (frequency) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease The value of the frequency multiplied by severity for the participant/subject having to void within 2 hours of last voiding (frequency) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have to void within two hours of last voiding? Frequency Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10076 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - fatigue limit activity severity score NMSSFatgLmtActSevScore The severity of fatigue (tiredness) or lack of energy (not slowness) that limits the participant/subject daytime activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of fatigue (tiredness) or lack of energy (not slowness) that limits the participant/subject daytime activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does fatigue tiredness or lack of energy not slowness limit the patient's daytime activities? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10119 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - forget event frequency NMSSFrgetEvntFreq The frequency of the participant/subject forgetting things that he/she has been told a short time ago or events that happened in the last few days as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject forgetting things that he/she has been told a short time ago or events that happened in the last few days as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient forget things that he she has been told a short time ago or events that happened in the last few days? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10151 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - sex function total score NMSSSexFuncTotalScore The total score for Domain 8: Sexual function as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The total score for Domain 8: Sexual function as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Score Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10087 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - lost interest frequency NMSSLostIntrstFreq The frequency of the participant/subject losing interest in his/her surroundings as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject losing interest in his/her surroundings as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Has the patient lost interest in his her surroundings 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10130 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - difficulty swallow frequency severity value NMSSDfcltySwllwFreqSevVal The value of the frequency multiplied by severity for the participant/subject having difficulty swallowing as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject having difficulty swallowing as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have difficulty swallowing? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10066 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - dizziness severity score NMSSDzySevScore The severity of the participant/subject experiencing light-headedness, dizziness, weakness on standing from sitting or lying position as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject experiencing light-headedness, dizziness, weakness on standing from sitting or lying position as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient experience light-headedness dizziness weakness on standing from sitting or lying position? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10162 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - excess sweat frequency NMSSExcsSweatFreq The frequency of the participant/subject experiencing excessive sweating (not related to hot weather) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject experiencing excessive sweating (not related to hot weather) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient experience excessive sweating not related to hot weather? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10098 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - flat mood severity score NMSSFlatMoodSevScore The severity of the participant/subject having flat moods without the normal "highs" and "lows" as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject having flat moods without the normal "highs" and "lows" as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have flat moods without the normal highs and lows? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10109 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - belief not true frequency NMSSBelfNotTrueFreq The frequency of the participant/subject having beliefs that you know are not true. For example, about being harmed, being robbed or being unfaithful as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject having beliefs that you know are not true. For example, about being harmed, being robbed or being unfaithful as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have beliefs that you know are not true? For example about being harmed being robbed or being unfaithful? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10141 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - night urine severity score NMSSNightUrnSevScore The severity of the participant/subject having to get up regularly at night to pass urine. (nocturia) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject having to get up regularly at night to pass urine. (nocturia) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have to get up regularly at night to pass urine? Nocturia 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10077 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - fatigue limit activity frequency NMSSFatgLmtActFreq The frequency of fatigue (tiredness) or lack of energy (not slowness) that limits the participant/subject daytime activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of fatigue (tiredness) or lack of energy (not slowness) that limits the participant/subject daytime activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does fatigue tiredness or lack of energy not slowness limit the patient's daytime activities? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10120 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - forget event frequency severity value NMSSFrgetEvntFreqSevVal The value of the frequency multiplied by severity for the participant/subject forgetting things that he/she has been told a short time ago or events that happened in the last few days as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the subject forgetting things that he/she has been told a short time ago or events that happened in the last few days as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient forget things that he she has been told a short time ago or events that happened in the last few days? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10152 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - pain severity score NMSSPainSevScore The severity of the participant/subject suffering from pain not explained by other known conditions. Related to intake of drugs and is relieved by antiparkinson drugs as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject suffering from pain not explained by other known conditions. Related to intake of drugs and is relieved by antiparkinson drugs as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient suffer from pain not explained by other known conditions? Is it related to intake of drugs and is it relieved by antiparkinson drugs? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10088 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - lost interest frequency severity value NMSSLostIntrstFreqSevVal The value of the frequency multiplied by severity for the participant/subject losing interest in his/her surroundings as part of the Non-Motor Symptom assessment scale for Parkinson's Disease. The value of the frequency multiplied by severity for the participant/subject losing interest in his/her surroundings as part of the Non-Motor Symptom assessment scale for Parkinson's Disease. Has the patient lost interest in his her surroundings Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10131 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - suffer constipation severity score NMSSSffrConstptnSevScore The severity of the participant/subject suffering from constipation (bowel action less than 3 times weekly) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject suffering from constipation (bowel action less than 3 times weekly) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient suffer from constipation? Bowel action less than three times weekly. 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10067 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - dizziness frequency NMSSDzyFreq The frequency of the participant/subject experiencing light-headedness, dizziness, weakness on standing from sitting or lying position as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject experiencing light-headedness, dizziness, weakness on standing from sitting or lying position as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient experience light-headedness dizziness weakness on standing from sitting or lying position? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10163 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - excess sweat frequency severity value NMSSExcsSweatFreqSevVal The value of the frequency multiplied by severity for the participant/subject experiencing excessive sweating (not related to hot weather) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject experiencing excessive sweating (not related to hot weather) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient experience excessive sweating not related to hot weather? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10099 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - flat mood frequency NMSSFlatMoodFreq The frequency of the participant/subject having flat moods without the normal "highs" and "lows" as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject having flat moods without the normal "highs" and "lows" as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have flat moods without the normal highs and lows? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10110 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - belief not true frequency severity value NMSSBelfNotTrueFreqSevVal The value of the frequency multiplied by severity for the participant/subject having beliefs that you know are not true. For example, about being harmed, being robbed or being unfaithful as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject having beliefs that you know are not true, as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have beliefs that you know are not true? For example about being harmed being robbed or being unfaithful? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10142 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - night urine frequency NMSSNightUrnFreq The frequency of the participant/subject having to get up regularly at night to pass urine. (nocturia) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject having to get up regularly at night to pass urine. (nocturia) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have to get up regularly at night to pass urine? Nocturia 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10078 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - fatigue limit activity frequency severity value NMSSFatgLmtActFreqSevVal The value of the frequency multiplied by severity for the fatigue (tiredness) or lack of energy (not slowness) that limits the participant/subject daytime activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the fatigue (tiredness) or lack of energy (not slowness) that limits the participant/subject daytime activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does fatigue tiredness or lack of energy not slowness limit the patient's daytime activities? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10121 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - forget do thing severity score NMSSFrgetDoThngSevScore The severity of the participant forgetting to do things. For example, take tablets or turn off domestic appliances as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant forgetting to do things. For example, take tablets or turn off domestic appliances as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient forget to do things? For example take tablets or turn off domestic appliances. 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10153 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - pain frequency NMSSPainFreq The frequency of the participant/subject suffering from pain not explained by other known conditions. Related to intake of drugs and is relieved by antiparkinson drugs as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject suffering from pain not explained by other known conditions. Related to intake of drugs and is relieved by antiparkinson drugs as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient suffer from pain not explained by other known conditions? Is it related to intake of drugs and is it relieved by antiparkinson drugs? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10089 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - lost interest activity severity score NMSSLostIntrstActSevScore The severity of the participant/subject losing interest in doing things or lacking motivation to start new activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease. The severity of the participant/subject losing interest in doing things or lacking motivation to start new activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Has the patient lost interest in doing things or lack motivation to start new activities? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10132 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - suffer constipation frequency NMSSSffrConstptnFreq The frequency of the participant/subject suffering from constipation (bowel action less than 3 times weekly) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject suffering from constipation (bowel action less than 3 times weekly) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient suffer from constipation? Bowel action less than three times weekly. 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10068 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - dizziness frequency severity value NMSSDzyFreqSevVal The value of the frequency multiplied by severity for participant/subject experiencing light-headedness, dizziness, weakness on standing from sitting or lying position as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for participant/subject experiencing light-headedness, dizziness, weakness on standing from sitting or lying position as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient experience light-headedness dizziness weakness on standing from sitting or lying position? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10164 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - miscellaneous total score NMSSMiscTotalScore The total score for Domain 9: Miscellaneous as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The total score for Domain 9: Miscellaneous as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Score Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10100 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - flat mood frequency severity value NMSSFlatMoodFreqSevVal The value of the frequency multiplied by severity for the participant/subject having flat moods without the normal "highs" and "lows" as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject having flat moods without the normal "highs" and "lows" as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have flat moods without the normal highs and lows? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10111 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - double vision severity score NMSSDblVisSevScore The severity of the participant/subject experiencing double vision. 2 separate real objects and not blurred vision as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject experiencing double vision. 2 separate real objects and not blurred vision as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient experience double vision? 2 separate real objects and not blurred vision 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10143 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - night urine frequency severity value NMSSNightUrnFreqSevVal The value of the frequency multiplied by severity for the participant/subject having to get up regularly at night to pass urine. (nocturia) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject having to get up regularly at night to pass urine. (nocturia) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have to get up regularly at night to pass urine? Nocturia Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10079 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - difficulty sleeping severity score NMSSDfcltySleepSevScore The severity of the participant/subject having difficulties falling or staying asleep as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject having difficulties falling or staying asleep as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have difficulties falling or staying asleep? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10122 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - forget do thing frequency NMSSFrgetDoThngFreq The frequency of the participant/subject forgetting to do things. For example, take tablets or turn off domestic appliances as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject forgetting to do things. For example, take tablets or turn off domestic appliances as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient forget to do things? For example take tablets or turn off domestic appliances. 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10154 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - pain frequency severity value NMSSPainFreqSevVal The value of the frequency multiplied by severity for the participant/subject suffering from pain not explained by other known conditions. Related to intake of drugs and is relieved by antiparkinson drugs as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject suffering from pain not explained by other known conditions. Related to intake of drugs and is relieved by antiparkinson drugs as part of the Non-Motor Symptom assessment scale Does the patient suffer from pain not explained by other known conditions? Is it related to intake of drugs and is it relieved by antiparkinson drugs? Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10090 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - lost interest activity frequency NMSSLostIntrstActFreq The frequency of the participant/subject losing interest in doing things or lacking motivation to start new activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease. The frequency of the participant/subject losing interest in doing things or lacking motivation to start new activities as part of the Non-Motor Symptom assessment scale for Parkinson's Disease. Has the patient lost interest in doing things or lack motivation to start new activities? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10133 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - suffer constipation frequency severity value NMSSSffrConstptnFreqSevVal The value of the frequency multiplied by severity for the participant/subject suffering from constipation (bowel action less than 3 times weekly) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject suffering from constipation (bowel action less than 3 times weekly) as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient suffer from constipation? Bowel action less than three times weekly. Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10069 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - fall faint severity score NMSSFallFaintSevScore The severity of the participant/subject falling because of fainting or blacking out as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject falling because of fainting or blacking out as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient fall because of fainting or blacking out? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10165 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - total score NMSSTotalScore The total score for the NMSS as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The total score for the NMSS as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Total Score Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10101 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - lack pleasure severity score NMSSLackPleasrSevScore The severity of the participant/subject having difficulty in experiencing pleasure from their usual activities or report that they lack pleasure as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The severity of the participant/subject having difficulty in experiencing pleasure from their usual activities or report that they lack pleasure as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have difficulty in experiencing pleasure from their usual activities or report that they lack pleasure? 0;1;2;3 None;mild: symptoms present but causes little distress or disturbance to patient;moderate: some distress or disturbance to patient;severe: major source of distress or disturbance to patient Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10112 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - double vision frequency NMSSDblVisFreq The frequency of the participant/subject experiencing double vision. 2 separate real objects and not blurred vision as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject experiencing double vision. 2 separate real objects and not blurred vision as part of the Non-Motor Symptom assessment scale for Parkinson's Disease. Does the patient experience double vision? 2 separate real objects and not blurred vision 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10144 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - urinary total score NMSSUrnryTotalScore The total score for Domain 7: Urinary as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The total score for Domain 7: Urinary as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Score Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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C10080 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - difficulty sleeping frequency NMSSDfcltySleepFreq The frequency of the participant/subject having difficulties falling or staying asleep as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The frequency of the participant/subject having difficulties falling or staying asleep as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient have difficulties falling or staying asleep? 1;2;3;4 rarely (<1/wk);often (1/wk);frequent (several times per week);very frequent (daily or all the time) Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

Single Pre-Defined Value Selected

C10123 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) - forget do thing frequency severity value NMSSFrgetDoThngFreqSevVal The value of the frequency multiplied by severity for the participant/subject forgetting to do things. For example, take tablets or turn off domestic appliances as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). The value of the frequency multiplied by severity for the participant/subject forgetting to do things. For example, take tablets or turn off domestic appliances as part of the Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS). Does the patient forget to do things? For example take tablets or turn off domestic appliances. Numeric Values Martinex-Martin P, Rodriguez-Blazquez C, Bhattacharya KB, et al. International Study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson Disease. Neurology 2009; 73:1584-1591. Adult Supplemental 3.00 2013-07-22 09:34:41.527 Non-Motor Symptom assessment scale for Parkinson's Disease (NMSS) Other Non-Motor Outcomes and End Points

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CSV