CDE Detailed Report

Disease: Chiari I Malformation
Sub-Domain: General Health History
CRF: CMI - Hereditary Disorder of Connective Tissue Screening (1)

Displaying 1 - 19 of 19
CDE ID CDE Name Variable Name Definition Short Description Additional Notes (Question Text) Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guideline) Sub Domain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C01521 Heart rate HeartRate The participant/subject's pulse or number of contractions (heart beats) per minute The participant/subject's pulse or number of contractions (heart beats) per minute Heart rate Numeric Values Adult;Pediatric Supplemental 3.00 2013-08-28 16:08:00.453 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Free-Form Entry

0 300 beats per minute 2767073
C21688 Beighton Score - Motion palm flat leg straight score BSMotPlmFltLegStrghtScore Score of ability of completing the motion palm flat and leg straight as part of the Beighton Score Score of ability of completing the motion palm flat and leg straight as part of the Beighton Score Palms flat to floor with legs straight Numeric Values Adult;Pediatric Supplemental 1.00 2016-05-26 12:57:21.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

C01522 Height measurement HgtMeasr Measurement of participant's/subject's height. Measurement of participant's/subject's height. Height measurement Numeric Values Adult;Pediatric Supplemental 3.00 2013-08-28 16:08:00.453 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Free-Form Entry

0 400 centimeter 649
C21689 Beighton Score - Total score BSTotalScore Total score as related to the Beighton Score Total score of Beighton Score Total score Numeric Values Adult;Pediatric Supplemental-Highly Recommended 1.00 2016-05-26 13:04:14.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Free-Form Entry

1 9 points
C01565 Blood pressure systolic measurement BldPressrSystMeasr Measurement of pressure of the participant's/subject's blood against the artery walls during systole (the contraction phase) in millimeters of mercury (mmHg) Measurement of pressure of the participant's/subject's blood against the artery walls during systole (the contraction phase) in millimeters of mercury (mmHg) BP systolic Numeric Values Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Free-Form Entry

0 300 millimeter of mercury 2004289 C25298
C22402 Hereditary disorder connective tissue diagnosis indicator HDCTDiagnosInd The indicator related to personal or family history of double jointedness or excessive joint flexibility or dislocations, also known as Hereditary Disorder of Connective Tissue (HDCT). The indicator related to personal or family history of double jointedness or excessive joint flexibility or dislocations, also known as Hereditary Disorder of Connective Tissue (HDCT). Known hereditary connective tissue disorder No;Yes No;Yes Alphanumeric Adult;Pediatric Supplemental-Highly Recommended 1.00 2016-06-10 10:04:38.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

C01582 Height unit of measure HgtUOM Unit of measure for the height numerical value for subject/participant Unit of measure for the height numerical value for subject/participant Height unit of measure Inches Inches Alphanumeric Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

2538920
C22433 Medical history aortic root enlargement indicator MedHistAorRootElargeInd The indicator related to any medical history of the enlargement of the subject's aortic root. The indicator related to any medical history of the enlargement of the subject's aortic root. Aortic root dilation No;Yes;Unknown No;Yes;Unknown Alphanumeric Adult;Pediatric Supplemental-Highly Recommended 1.00 2016-06-10 12:56:04.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

C10724 Echocardiogram performed date and time EchcrdgrmPerfrmDateTime Date (and time, if applicable and known) the echocardiography was performed Date (and time, if applicable and known) the echocardiography was performed Echocardiogram Date Date or Date & Time Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Free-Form Entry

C22775 Hereditary disorder connective tissue diagnosis type HereDisConnTissDiagTyp The type related to hereditary disorder of connective tissues. The type related to hereditary disorder of connective tissues. Hereditary Disorders of Connective Tissue Diagnoses Classical EDS;EDS – mild classical vs. hypermobile;Hypermobile EDS;Marfan;MASS phenotype;Stickler Syndrome;Loeys-Dietz Syndrome;Evidence of possible HDCT;Associated conditions Classical EDS (type I & II – skin features);EDS – mild classical vs. hypermobile (borderline skin findings);Hypermobile EDS (type III – absence of skin features) "Benign joint hypermobility";Marfan (AS/Ht > 1.05, pectus ab, aortic dil., dural ectasia, ectopia lentis);MASS phenotype (myopia, mitral valve prolapse, aortic dil., skin & skeletal features);Stickler Syndrome (collagen type 2 or 11, myopia, hearing loss, osteoarthritis, cleft palate);Loeys-Dietz Syndrome (hypertelorism, bifid uvula, aneurysms);Evidence of possible HDCT (Unknown/Unspecified);Associated conditions Alphanumeric Adult;Pediatric Supplemental-Highly Recommended 1.00 2016-10-19 12:03:19.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Multiple Pre-Defined Values Selected

C12175 Dual X-ray absorptiometry performed date DEXAPerfrmDate The date the Dual X-ray absorptiometry (DEXA) was performed The date the Dual X-ray absorptiometry (DEXA) was performed DEXA Scan Date Date or Date & Time Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Free-Form Entry

C22776 Hereditary disorder type HereditaryDisorderTyp The type related to hereditary disorder of connective tissues. The type related to hereditary disorder of connective tissues. Assessment Fibromyalgia Syndrome;Acquired/Autoimmune Connective Tissue Disorders;Osteoarthritis/Degenerative Joint Disease;Hereditary Disorders of Connective Tissue Diagnoses Fibromyalgia Syndrome;Acquired/Autoimmune Connective Tissue Disorders;Osteoarthritis/Degenerative Joint Disease;Hereditary Disorders of Connective Tissue Diagnoses Alphanumeric Adult;Pediatric Supplemental-Highly Recommended 1.00 2016-10-19 12:03:19.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Multiple Pre-Defined Values Selected

C12875 Echocardiogram mitral valve prolapse indicator EchcrdgrmMitrlValvProlapseInd Assessment with echocardiography of the absence or presence of prolapse of the mitral valve, often with regurgitation, associated with myxomatous proliferation of the leaflets of the mitral valve. Assessment with echocardiography of the absence or presence of prolapse of the mitral valve, often with regurgitation, associated with myxomatous proliferation of the leaflets of the mitral valve. Mitral valve prolapsed Yes;No;Unknown Yes;No;Unknown Alphanumeric Adult;Pediatric Supplemental-Highly Recommended 3.00 2013-07-24 11:38:01.2 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

C21684 Beighton Score - Motion thumb forearm assessment score BSMotThmbForarmAsmntScore Score/Assessment of the motion thumb to forearm as part of the Beighton Score Score/Assessment of the motion thumb to forearm as part of the Beighton Score Thumb to forearm 0;1R;1L;2 0;1 Right;1 Left;2 Numeric Values Adult;Pediatric Supplemental 1.00 2016-05-26 11:31:16.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

C21685 Beighton Score - Motion finger bend back score BSMotFngBndBckScore Score/Assessment of Motion to bend finger back as part of the Beighton Score Score/Assessment of Motion to bend finger back as part of the Beighton Score Bending little fingers back 90 degrees or more 0;1R;1L;2 0;1 Right;1 Left;2 Numeric Values Adult;Pediatric Supplemental 1.00 2016-05-26 12:08:02.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

C00008 Age value AgeVal Value for participant/subject's age, calculated as elapsed time since the birth of the participant/subject. Value for participant/subject's age, calculated as elapsed time since the birth of the participant/subject. Age at dx Numeric Values Adult;Pediatric Supplemental 3.00 2013-08-28 16:08:00.453 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Free-Form Entry

0 1800 month
C21686 Beighton Score - Motion elbow hyperextend score BSMotElbHypExtScore Score/assessment of ability to complete the motion hyperextended elbow as part of the Beighton Score Score/assessment of ability to complete the motion hyperextended elbow as part of the Beighton Score Elbows hyperextended to 10 degrees or more 0;1R;1L;2 0;1 Right;1 Left;2 Numeric Values Adult;Pediatric Supplemental 1.00 2016-05-26 12:29:00.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

C01507 Blood pressure diastolic measurement BldPressrDiastlMeasr Measurement of pressure of the participant's/subject's blood against the artery walls during diastole (the relaxation phase) in millimeters of mercury (mmHg) Measurement of pressure of the participant's/subject's blood against the artery walls during diastole (the relaxation phase) in millimeters of mercury (mmHg) BP diastolic Numeric Values Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Free-Form Entry

0 300 millimeter of mercury 2004291
C21687 Beighton Score - Motion knee hyperextend score BSMotKnHypExtScore Score/assessment of ability to complete the Motion hyperextended knee as part of Beighton Score Score/assessment of ability to complete the Motion hyperextended knee as part of Beighton Score Knees hyperextended to 10 degrees or more 0;1R;1L;2 0;1 Right;1 Left;2 Numeric Values Adult;Pediatric Supplemental 1.00 2016-05-26 12:35:37.0 CMI - Hereditary Disorder of Connective Tissue Screening (1) General Health History Participant History and Family History

Single Pre-Defined Value Selected

CSV