CDE Detailed Report
Subdomain Name: Laboratory Tests and Biospecimens/Biomarkers
CRF: files
Displaying 51 - 100 of 166
CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
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C12269 | Biopsy and autopsy immunohistochemical immunofluorescence assays performed | BpApImnhschmImnflrsncAssyPerf | List of stains used | List of stains used | Immunohistochemical/ Immunofluorescence assays performed | Alphanumeric |
List the stains used based upon answers in question 3 |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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C19963 | Immunohistochemistry beta dystroglycan status | IHCBetaDystroglyStat | The status of Beta dystroglycan in immunohistochemistry | The status of Beta dystroglycan in immunohistochemistry | Beta dystroglycan | Absent;Reduced;Normal | Absent;Reduced;Normal | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19974 | Immunohistochemistry inflammatory mypoathy panel stain type | InflamMyoPanImmStainTyp | Type of inflammatory myopathy panel used | Type of inflammatory myopathy panel used | Inflammatory myopathy panel | CD3;CD45;CD4;CD8;CD20;CD138;CD68;C5b-9;Major histocompatibility complex | CD3;CD45;CD4;CD8;CD20;CD138;CD68;C5b-9;Major histocompatibility complex | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19910 | Biopsy and autopsy trichome red inclusions status | BpApRedInclusTrichStat | Red inclusions on trichome status | Red inclusions on trichome status | Red inclusions on trichome | Absent;Sparse;Moderate | Absent;Sparse;Moderate | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C20325 | Biopsy and autopsy inflammation description type | BpApInflamDescTyp | The descriptions as related to perivascular inflammation is focused around blood vessels, whereas diffuse inflammation also spreads across the muscle tissue. Inflammatory cells identified include lymphocytes, neutrophils, macrophages, and eosinophils. At times, microorganisms can be identified and should be mentioned | The descriptions as related to perivascular inflammation is focused around blood vessels, whereas diffuse inflammation also spreads across the muscle tissue. Inflammatory cells identified include lymphocytes, neutrophils, macrophages, and eosinophils. At times, microorganisms can be identified and should be mentione | Inflammation, specify | Distribution;Associated with myofiber damage;Associated with non-necrotic myofiber;Granulomas;Inflammatory cells identified | Distribution;Associated with myofiber damage;Associated with non-necrotic myofiber;Granulomas;Inflammatory cells identified | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-17 11:38:01.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12235 | Histochemical stains used type | HistchmclStainUseTyp | Type of standard histochemical stains used on the tissue specimen | Type of standard histochemical stains used on the tissue specimen | Which standard histochemical stains were used? | H and E;Other, specify;NADH;SDH/COX;Oil Red O;ATPase 4.3;ATPase 4.6;ATPase 9.4;Acid phosphatase;Phosphorylase;Phosphofructokinase;Sudan black;SDH;COX;Esterase;Gomori trichrome;Myoadenylate deaminase;PAS | H and E;Other, specify;NADH;SDH/COX;Oil Red O;ATPase 4.3;ATPase 4.6;ATPase 9.4;Acid phosphatase;Phosphorylase;Phosphofructokinase;Sudan black;SDH;COX;Esterase;Gomori trichrome;Myoadenylate deaminase;PAS | Alphanumeric |
Choose all that apply |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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C19942 | Biopsy and autopsy granulomas type | BpApGranTyp | Type of granulomas of inflammation | Type of granulomas of inflammation | Granulomas | Necrotizing;Non-necrotizing;Giant cells present;Foreign material present | Necrotizing;Non-necrotizing;Giant cells present;Foreign material present | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12528 | Biopsy and autopsy nemaline rods restricted to one fiber text | BpApNemaRodRstrct1FibTxt | Nemaline rods restricted to one fiber text | Nemaline rods restricted to one fiber text | Restricted to one fiber type, specify which | Numeric Values |
Only answered if "Nemaline rod , restricted to one fiber type" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Free-Form Entry |
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C19889 | Symptom presentation weakness distribution type | SymptmPresentWeakDisTyp | Weakness distribution symptoms participant/ subject shows at presentation | Weakness distribution symptoms participant/ subject shows at presentation | Weakness (distribution) | Asymmetrical;Symmetrical;Proximal;Distal;Limb girdle;Facioscapulohermal;Neck;Paraspinal;Finger flexion;Other, specify | Asymmetrical;Symmetrical;Proximal;Distal;Limb girdle;Facioscapulohermal;Neck;Paraspinal;Finger flexion;Other, specify | Alphanumeric |
Check all that apply. |
No references available | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19985 | Immunohistochemistry CD45 presence status | IHCCD45PresStat | The status of the presence of CD45 in immunohistochemistry | The status of the presence of CD45 in immunohistochemistry | CD45 | Absent;Present | Absent;Present | Alphanumeric |
If present; specify the percent of lymphocytes |
Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19921 | Biopsy and autopsy central cores estimated percentage value | BpApCentralCoreEstCt | Central cores estimated percentage value | Central cores estimated percentage value | Moderate (present in:) | Numeric Values | No references available | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Free-Form Entry |
0 | 100 | percent | ||||||||
C12252 | Biopsy and autopsy fiber size variation result type | BpApFibSizeVariResltTyp | Distribution of the atrophic fibers | Distribution of the atrophic fiber | Specify | Single fibers;Groups of fibers;Type 1 fibers only;Type 2 fibers only;Perifascicular distribution | Single fibers;Groups of fibers;Type 1 fibers only;Type 2 fibers only;Perifascicular distribution | Alphanumeric |
Only answered if "Subsets of fibers, leading to excessive variation in fiber size, specify" is answered for "Atrophy/Hypotrophy". Choose all that apply |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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C19953 | Immunohistochemistry dystrophin C terminus status | IHCDysCTerminStat | The status of dystrophin C terminus (DYS2) in immunohistochemistry | The status of dystrophin C terminus (DYS2) in immunohistochemistry | Dystrophin C terminus (DYS2) | Absent;Reduced;Cytoplasmic;Normal | Absent;Reduced;Cytoplasmic;Normal | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19900 | Laboratory findings autoantibody known text | LabFinAutoAntiKnownText | Text of the known autoantibodies in patient | Text of the known autoantibodies in patient | Known autoantibodies in patient | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations | 4000 |
Free-Form Entry |
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C19996 | Biopsy and autopsy additional immunohistochemical assays performed text | BpApAddImmhistchmAssPerText | Specify any additional immunohistochemical/immunoflourescence assays performed | Specify any additional immunohistochemical/immunoflourescence assays performed | Additional immunohistochemical/immunoflourescence assays performed | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations | 4000 |
Free-Form Entry |
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C00035 | Gender type | GenderTyp | Self-reported gender of the participant/subject | Self-reported gender of the participant/subjec | Gender of Patient | Alphanumeric |
Choose one. Response is obtained by report of the participant/subject or caretaker. |
The NIH Guidelines on Inclusion of Women and Minorities as Subjects in Clinical Research: The Office of Management and Budget Directive No. 15 (http://grants.nih.gov/grants/funding/women_min/guidelines_update.htm) | Adult;Pediatric | Core | 3.00 | 2013-08-28 16:08:00.453 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
2200604 | |||||||||
C19932 | Biopsy and autopsy ring fibers status | BpApRingFibStat | Ring fibers status in biopsy/autopsy | Ring fibers status in biopsy/autopsy | Ring fibers | Absent;Sparse;Moderate | Absent;Sparse;Moderate | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12276 | Biopsy and autopsy mitochondria abnormality type | BpApMitochAbnrmlyTyp | Type of mitochondria abnormality in muscle biopsy | Type of mitochondria abnormality in muscle biopsy | Abnormalities noted in Mitochondria, specify | Abnormal shape;Abnormal location;Abnormal numbers;Abnormal architecture;Abnormal size | Abnormal shape;Abnormal location, specify;Abnormal numbers;Abnormal architecture;Abnormal size | Alphanumeric |
Choose all that apply. Only answered if "Mitochondria" is answered for "Abnormalities noted in" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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C19964 | Immunohistochemistry alpha sarcoglycan status | IHCAlpSarcoglyStat | The status of Alpha sarcoglycan in immunohistochemistry | The status of Alpha sarcoglycan in immunohistochemistry | Alpha sarcoglycan | Absent;Reduced;Normal | Absent;Reduced;Normal | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19975 | Immunohistochemistry CD3 presence status | IHCCD3PresStat | The status of the presence of CD3 in immunohistochemistry | The status of the presence of CD3 in immunohistochemistry | CD3 | Absent;Present | Absent;Present | Alphanumeric |
If present; specify the percent of lymphocytes |
Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19911 | Biopsy and autopsy trichome red inclusions estimated percentage count | BpApRedInclusTrichEstCt | Red inclusions on trichome estimated percentage value | Red inclusions on trichome estimated percentage value | Moderate (present in:) | Numeric Values | No references available | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Free-Form Entry |
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C20326 | Biopsy autopsy excessive glycogen status | BpApExessGlycoStat | The status related to glycogen storage pathology which involves excess PAS+ material that is easily identifiable on light microscopy and is evident on other stains including H and E. Mild glycogen storage pathology is difficult to determine at the light microscopic level and may only be evident on PAS stain or electron microscopy | The status related to glycogen storage pathology which involves excess PAS+ material that is easily identifiable on light microscopy and is evident on other stains including H and E. Mild glycogen storage pathology is difficult to determine at the light microscopic level and may only be evident on PAS stain or electron microscop | Excessive glycogen | Absent;Mild;Marked | Absent;Mild;Marked | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-18 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12238 | Biopsy and autopsy epon embedded tissue abnormalities location type | BpApEponEmbedTissAbnrmlLocTyp | Type of abnormality observed microscopically in epon-embedded tissue specimen | Type of abnormality observed microscopically in epon-embedded tissue specimen | Abnormalities noted in | Nuclei;Contractile apparatus;Sarcotubular organization;Mitochondria, specify;Basal lamina;Satellite cells;Intramuscular nerve twigs | Nuclei;Contractile apparatus;Sarcotubular organization;Mitochondria, specify (choose all that apply);Basal lamina;Satellite cells;Intramuscular nerve twigs | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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C19943 | Biopsy and autopsy intramuscular nerve branche status | BpApIntramusNervBranchStat | The status of the presence of intramuscular nerve branches | The status of the presence of intramuscular nerve branches | Intramuscular nerve branches | Absent;Present | Absent;Present | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12529 | Biopsy and autopsy ragged red fibers estimated count | BpApRggdRdFibEstCt | Ragged red fibers estimated number | Ragged red fibers estimated number | Moderate (present in:) | Numeric Values |
Only answered if "Ragged red fibers" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Free-Form Entry |
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C19890 | Symptom presentation weakness distribution other text | SymptmPresentWeakDisTypOTH | The free-text field to describe other symptoms participant/ subject shows at presentation | The free-text field to describe other symptoms participant/ subject shows at presentation | Other | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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C19986 | Immunohistochemistry CD45 percentage value | IHCCD45PercentVal | Percent value of CD45 | Percent value of CD45 | Present in | Numeric Values | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Free-Form Entry |
0 | 100 | percent | |||||||||
C19922 | Biopsy and autopsy minicores status | BpApMinicoreStat | Minicores status in biopsy | Minicores status in biopsy | Minicores | Absent;Sparse;Moderate | Absent;Sparse;Moderate | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12253 | Biopsy and autopsy atrophy or hyportrophy fiber shape type | BpApAtrphyHyptrphyFibShpTyp | Atrophic/ hypertrophic fiber shape | Atrophic/ hypertrophic fiber shape | Atrophic/hypotrophic fiber shape | Angulated;Round | Angulated;Round | Alphanumeric |
Only answered if "Atrophic/Hypertrophic fiber shape, specify" is answered for "Atrophy/Hypotrophy" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19954 | Immunohistochemistry dystrophin N terminus status | IHCDysNTerminStat | The status of dystrophin N terminus (DYS3) in immunohistochemistry | The status of dystrophin N terminus (DYS3) in immunohistochemistry | Dystrophin N terminus (DYS3) | Absent;Reduced;Cytoplasmic;Normal | Absent;Reduced;Cytoplasmic;Normal | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19965 | Immunohistochemistry beta sarcoglycan status | IHCBetaSarcoglyStat | The status of Beta sarcoglycan in immunohistochemistry | The status of Beta sarcoglycan in immunohistochemistry | Beta sarcoglycan | Absent;Reduced;Normal | Absent;Reduced;Normal | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19901 | Imaging electromyography findings status | ImgEMGFindStatus | Status of the electromyography (EMG) findings of patient | Status of the electromyography (EMG) findings of patient | EMG findings | Not known;Myopathic;Neuropathic | Not known;Myopathic;Neuropathic | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12226 | Specimen source type | SpecmnSourcTyp | Type of specimen collection source | Type of specimen collection source | Is this a biopsy or autopsy specimen? | Biopsy;Autopsy | Biopsy;Autopsy | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental-Highly Recommended | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19933 | Biopsy and autopsy ring fibers estimated percentage value | BpApRingFibEstCt | Ring fibers estimated percentage value | Ring fibers estimated percentage value | Moderate (present in:) | Numeric Values | No references available | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Free-Form Entry |
0 | 100 | percent | ||||||||
C12517 | Fatty replacement severity status | FttyReplcmntSeverStat | Severity of the Fatty replacement muscle diagnostic abnormalities | Severity of the fatty replacement muscle diagnostic abnormalities | Fatty infiltration | Mild;Moderate;Severe | Mild;Moderate;Severe | Alphanumeric |
No instructions available |
No references available | Adult | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19976 | Immunohistochemistry CD3 percentage value | IHCCD3PercentVal | Percent value of CD3 | Percent value of CD3 | Present in | Numeric Values | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Free-Form Entry |
0 | 100 | percent | |||||||||
C19912 | Biopsy and autopsy rimmed vacuoles status | BpApRimmVacStat | Rimmed vacuoles status in tissue | Rimmed vacuoles status in tissue | Rimmed vacuoles | Absent;Sparse;Moderate | Absent;Sparse;Moderate | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C20327 | Biopsy autopsy excessive intracellular lipid status | BpApExessIntraceLipidStat | The status related to excessive intracellular lipid storage pathology which involves excess Oil Red O+ material that is easily identifiable on light microscopy and is evident on other stains including H and E | The status related to excessive intracellular lipid storage pathology which involves excess Oil Red O+ material that is easily identifiable on light microscopy and is evident on other stains including H and | Excessive intracellular lipid | Absent;Mild;Marked | Absent;Mild;Marked | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-18 08:54:08.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12239 | Electron microscopy performed indicator | ElectrnMicroPerfInd | Indicator of whether electron microscopy was performed | Indicator of whether electron microscopy was performed | Was electron microscopy performed? | Yes;No;Unknown | Yes;No;Unknown | Alphanumeric |
No instructions available |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19944 | Biopsy and autopsy intramuscular nerve branche type | BpApIntramusNervBranchTyp | Type of intramuscular nerve branches | Type of intramuscular nerve branches | Specify | Decreased axonal density;Increased endoneurial fibrosis;Abnormality of myelination;Abnormal structures;Muscle spindles | Decreased axonal density;Increased endoneurial fibrosis;Abnormality of myelination;Abnormal structures;Muscle spindles | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C12530 | Biopsy autopsy COX-negative fibers estimated count | BpApCOXNegFibEstCt | COX-negative fibers estimated number | COX-negative fibers estimated number | Moderate (present in:) | Alphanumeric |
Only answered if "COX-negative fibers" is answered for "Myopathy-associated pathological structures" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-25 08:54:08.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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C19891 | Symptom presentation other muscle symptoms type | SymptmPresentOthMusSympTyp | Other muscle symptoms participant/ subject shows at presentation | Other muscle symptoms participant/ subject shows at presentation | Other muscle symptoms | Hypotonia (floppiness);Muscle pain;Exercise intolerance;Episodic muscle pain/cramping;Rhabdomyolysis;Contractures | Hypotonia (floppiness);Muscle pain;Exercise intolerance;Episodic muscle pain/cramping;Rhabdomyolysis;Contractures | Alphanumeric |
Check all that apply. |
Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Multiple Pre-Defined Values Selected |
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C19987 | Immunohistochemistry CD68 presence status | IHCCD68PresStat | The status of the presence of CD68 in immunohistochemistry | The status of the presence of CD68 in immunohistochemistry | CD68 | Absent;Present | Absent;Present | Alphanumeric |
If present; specify the percent of lymphocytes |
Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19923 | Biopsy and autopsy minicores estimated percentage value | BpApMinicoreEstCt | Minicores estimated percent count | Minicores estimated percent count | Moderate (present in:) | Numeric Values | No references available | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Free-Form Entry |
0 | 100 | percent | ||||||||
C12254 | Biopsy and autopsy myopathy-associated pathological structures type | BpApMyopAsscPathoStrucTyp | The type of myopathy-associated pathological structures seen in the histology of the biopsy or autopsy specimen | The type of myopathy-associated pathological structures seen in the histology of the biopsy or autopsy specimen | Myopathy-associated pathological structures, specify | Central nuclei;Nemaline rods;Ragged red fibers;COX-negative fibers;Central cores;Minicores;Marked hypertrophy of type 1 fibers;Blood vessel deposits suggestive of amyloid;Core-like lesions;Internal nuclei;Lobulated fibers;Moth-eaten fibers;Non-rimmed vacuoles;Red inclusions on trichrome;Rimmed vacuoles;Ring fibers;Split fibers;Strongly SDH-reactive blood vessels;Targetoid fibers;Tubular aggregates | Central nuclei;Nemaline rods;Ragged red fibers;COX-negative fibers;Central cores;Minicores;Marked hypertrophy of type 1 fibers;Blood vessel deposits suggestive of amyloid;Core-like lesions;Internal nuclei;Lobulated fibers;Moth-eaten fibers;Non-rimmed vacuoles;Red inclusions on trichrome;Rimmed vacuoles;Ring fibers;Split fibers;Strongly SDH-reactive blood vessels;Targetoid fibers;Tubular aggregates | Alphanumeric |
Only answered if "Myopathy-associated pathological structures" is answered for "Which of the following diagnostic abnormalities were noted on histochemical stains?" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19955 | Immunohistochemistry dystrophin status | IHCDystrophinStat | The status of dystrophin (BMD hotspot) in immunohistochemistry | The status of dystrophin (BMD hotspot) in immunohistochemistry | Dystrophin (BMD hotspot) | Absent;Reduced;Cytoplasmic;Normal | Absent;Reduced;Cytoplasmic;Normal | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19966 | Immunohistochemistry delta sarcoglycan status | IHCDeltaSarcoglyStat | The status of Delta sarcoglycan in immunohistochemistry | The status of Delta sarcoglycan in immunohistochemistry | Delta sarcoglycan | Absent;Reduced;Normal | Absent;Reduced;Normal | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |
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C19902 | Imaging electromyography findings text | ImagFindText | Text of imaging findings of patient | Text of imaging findings of patient | Imaging findings (brain/muscle) | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations | 255 |
Free-Form Entry |
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C12227 | Postmortem interval for autopsy specimen value | PstmrtmIntrvlApSpecmnVal | Interval in hours of time elapsed between death and the autopsy at which the tissue specimen was collected | Interval in hours of time elapsed between death and the autopsy at which the tissue specimen was collected | If this is an autopsy specimen what is the approximate postmortem interval? | Numeric Values |
Only answered if "Autopsy" is answered for "Is this a biopsy or autopsy specimen?" |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-24 11:38:01.2 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
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C19934 | Biopsy and autopsy split fibers status | BpApSplitFibStat | Split fibers status in biopsy/autopsy | Split fibers status in biopsy/autopsy | Split fibers | Absent;Sparse | Absent;Sparse | Alphanumeric | Adult;Pediatric | Supplemental | 1.00 | 2015-02-09 00:00:00.0 | Muscle Biopsies and Autopsy Tissue | Laboratory Tests and Biospecimens/Biomarkers | Assessments and Examinations |
Single Pre-Defined Value Selected |