CDE Detailed Report

Disease: content
Subdomain Name: Laboratory Tests and Biospecimens/Biomarkers
CRF: welcome

Displaying 151 - 166 of 166
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C19952 Immunohistochemistry dystrophin rod domain status IHCDysRodDomStat The status of dystrophin rod domain (DYS1) in immunohistochemistry The status of dystrophin rod domain (DYS1) in immunohistochemistry Dystrophin rod domain (DYS1) Absent;Reduced;Cytoplasmic;Normal Absent;Reduced;Cytoplasmic;Normal Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19963 Immunohistochemistry beta dystroglycan status IHCBetaDystroglyStat The status of Beta dystroglycan in immunohistochemistry The status of Beta dystroglycan in immunohistochemistry Beta dystroglycan Absent;Reduced;Normal Absent;Reduced;Normal Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19899 Elevated C reactive protein value ElevatCReactProtVal The elevated C-reactive protein value The elevated C-reactive protein value Patient Value Numeric Values

No instructions available

 No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

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C19995 Immunohistochemistry ubiquitin aggregate level status IHCUbiquitinAggregLvlStat Level of ubiquitin aggregate Level of ubiquitin aggregate Myotilin Normal;Increased Normal;Increased Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19931 Biopsy and autopsy tubular aggregates estimated percentage value BpApTubAggEstCt Tubular aggregates estimated percentage value Tubular aggregates estimated percentage value Moderate (present in:) Numeric Values No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Free-Form Entry

 0 100 percent
C12269 Biopsy and autopsy immunohistochemical immunofluorescence assays performed BpApImnhschmImnflrsncAssyPerf List of stains used List of stains used Immunohistochemical/ Immunofluorescence assays performed Alphanumeric

List the stains used based upon answers in question 3

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations 255

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C12528 Biopsy and autopsy nemaline rods restricted to one fiber text BpApNemaRodRstrct1FibTxt Nemaline rods restricted to one fiber text Nemaline rods restricted to one fiber text Restricted to one fiber type, specify which Numeric Values

Only answered if "Nemaline rod , restricted to one fiber type" is answered for "Myopathy-associated pathological structures"

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

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C19974 Immunohistochemistry inflammatory mypoathy panel stain type InflamMyoPanImmStainTyp Type of inflammatory myopathy panel used Type of inflammatory myopathy panel used Inflammatory myopathy panel CD3;CD45;CD4;CD8;CD20;CD138;CD68;C5b-9;Major histocompatibility complex CD3;CD45;CD4;CD8;CD20;CD138;CD68;C5b-9;Major histocompatibility complex Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19910 Biopsy and autopsy trichome red inclusions status BpApRedInclusTrichStat Red inclusions on trichome status Red inclusions on trichome status Red inclusions on trichome Absent;Sparse;Moderate Absent;Sparse;Moderate Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C12235 Histochemical stains used type HistchmclStainUseTyp Type of standard histochemical stains used on the tissue specimen Type of standard histochemical stains used on the tissue specimen Which standard histochemical stains were used? H and E;Other, specify;NADH;SDH/COX;Oil Red O;ATPase 4.3;ATPase 4.6;ATPase 9.4;Acid phosphatase;Phosphorylase;Phosphofructokinase;Sudan black;SDH;COX;Esterase;Gomori trichrome;Myoadenylate deaminase;PAS H and E;Other, specify;NADH;SDH/COX;Oil Red O;ATPase 4.3;ATPase 4.6;ATPase 9.4;Acid phosphatase;Phosphorylase;Phosphofructokinase;Sudan black;SDH;COX;Esterase;Gomori trichrome;Myoadenylate deaminase;PAS Alphanumeric

Choose all that apply

 No references available Adult;Pediatric Supplemental 3.00 2013-07-24 11:38:01.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Multiple Pre-Defined Values Selected
C19942 Biopsy and autopsy granulomas type BpApGranTyp Type of granulomas of inflammation Type of granulomas of inflammation Granulomas Necrotizing;Non-necrotizing;Giant cells present;Foreign material present Necrotizing;Non-necrotizing;Giant cells present;Foreign material present Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19889 Symptom presentation weakness distribution type SymptmPresentWeakDisTyp Weakness distribution symptoms participant/ subject shows at presentation Weakness distribution symptoms participant/ subject shows at presentation Weakness (distribution) Asymmetrical;Symmetrical;Proximal;Distal;Limb girdle;Facioscapulohermal;Neck;Paraspinal;Finger flexion;Other, specify Asymmetrical;Symmetrical;Proximal;Distal;Limb girdle;Facioscapulohermal;Neck;Paraspinal;Finger flexion;Other, specify Alphanumeric

Check all that apply.

 No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19985 Immunohistochemistry CD45 presence status IHCCD45PresStat The status of the presence of CD45 in immunohistochemistry The status of the presence of CD45 in immunohistochemistry CD45 Absent;Present Absent;Present Alphanumeric

If present; specify the percent of lymphocytes

 Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
C19921 Biopsy and autopsy central cores estimated percentage value BpApCentralCoreEstCt Central cores estimated percentage value Central cores estimated percentage value Moderate (present in:) Numeric Values No references available Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Free-Form Entry

 0 100 percent
C12252 Biopsy and autopsy fiber size variation result type BpApFibSizeVariResltTyp Distribution of the atrophic fibers Distribution of the atrophic fiber Specify Single fibers;Groups of fibers;Type 1 fibers only;Type 2 fibers only;Perifascicular distribution Single fibers;Groups of fibers;Type 1 fibers only;Type 2 fibers only;Perifascicular distribution Alphanumeric

Only answered if "Subsets of fibers, leading to excessive variation in fiber size, specify" is answered for "Atrophy/Hypotrophy". Choose all that apply

 No references available Adult;Pediatric Supplemental 3.00 2013-07-25 08:54:08.2 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Multiple Pre-Defined Values Selected
C19953 Immunohistochemistry dystrophin C terminus status IHCDysCTerminStat The status of dystrophin C terminus (DYS2) in immunohistochemistry The status of dystrophin C terminus (DYS2) in immunohistochemistry Dystrophin C terminus (DYS2) Absent;Reduced;Cytoplasmic;Normal Absent;Reduced;Cytoplasmic;Normal Alphanumeric Adult;Pediatric Supplemental 1.00 2015-02-09 00:00:00.0 Muscle Biopsies and Autopsy Tissue Laboratory Tests and Biospecimens/Biomarkers Assessments and Examinations

Single Pre-Defined Value Selected
CSV