CDE Detailed Report

Disease: system
Subdomain Name: General Health History
CRF: files

Displaying 51 - 51 of 51
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C19209 Pre-existing degenerative spine disorder specify anatomic site DgnrtvSpinDisordSpcfyAntmcSite Specifies anatomic site of pre-existing degenerative spine disorder Specifies anatomic site of pre-existing degenerative spine disorder Specify location Alphanumeric

Degenerative spine disorders present with aging. The most common disorders are lumbar (Abbas et al. 2010; Yasar et al. 2009) and cervical (Tracy & Bartleson 2010; Fehlings & Arvin 2009) spinal canal stenosis, spondylosis and degenerative systemic disorders (like diffuse idiopathic skeletal hyperostosis (DISH) and rheumatoid arthritis). These disorders typically develop slowly with the spinal cord often adapting to extensive morphological changes before notable
impairment. The onset of impairments is usually slow and insidious and therefore not noticed by individuals for a considerable time. However, the degenerative changes can increase susceptibility to spinal cord lesions from relatively minor insults, e.g. minor falls with mild extension/flexion trauma inducing a central cord syndrome (Matz et al. 2009).

Biering-S&Oslash;rensen F, Burns AS, Curt A, Harvey LA, Jane Mulcahey M, Nance PW,<br />Sherwood AM, Sisto SA. International spinal cord injury musculoskeletal basic<br />data set. Spinal Cord. 2012 Nov;50(11):797-802. doi: 10.1038/sc.2012.102. Adult;Pediatric Exploratory 1.00 2014-06-03 15:23:28.0 Medical History General Health History Participant History and Family History 4000

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