CDE Detailed Report

Disease: system
Subdomain Name: Other Clinical Data
CRF: files

Displaying 151 - 175 of 175
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C15064 Brain atrophy nucleus coeruleus globosum neuronal tangles (GNT) severity result BrAtNucCoerGloNeurTanSevReslt Quantitative result of the severity of GNT in the nucleus coeruleus Quantitative result of the severity of GNT in the nucleus coeruleu Present Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

Nucleus coeruleus

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Single Pre-Defined Value Selected

C14972 Macroscopical examination fixed brain source MacroExamFixedBrainSource The part(s) of the fixed brain used for macroscopical examination The part(s) of the fixed brain used for macroscopical examination Macroscopical examination Fixed Whole brain;Left half brain;Right half brain;Not available;Other, specify Whole brain;Left half brain;Right half brain;Not available;Other, specify Alphanumeric

Indicate the parts selected for evaluation

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C15096 Hemorrhages single or multiple vascular territories name HemSingMultiVascTerrName Name of the vascular territories where hemorrhages occur Name of the vascular territories where hemorrhages occur Vascular territories (ACA anterior cerebral artery; MCA middle cerebral artery; PCA posterior cerebral artery) ACA;MCA;PCA;Combined ACA=anterior cerebral artery;MCA=middle cerebral artery;PCA=posterior cerebral artery; Alphanumeric

No additional instructions

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C15107 Huntingtons Disease diagnosis grade HDDiagnosGrade The grade of severity of HD or amyloid angiopathy severity The grade of severity of HD or amyloid angiopathy severity Final Clinicopathological Diagnosis Grade 1;Grade 2;Grade 3;Grade 4 Grade 1;Grade 2;Grade 3;Grade 4 Alphanumeric

Only answered if "Huntington disease" or "Cerebral amyloid angiopathy" are answered for Final Clinicopathological diagnoses

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C15043 Brain atrophy thalamus neuronal loss indicator BrAtThalamusNeurLossInd Indicator of neuronal loss in the thalamus Indicator of neuronal loss in the thalamu Thalamus Neuronal loss No neuronal loss;Yes neuronal loss No neuronal loss;Yes neuronal loss Alphanumeric

No additional instructions

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C08157 Photograph macroscopic indicator PhotographsMacroscopicInd Indicator of whether macroscopic photographs were taken Indicator of whether macroscopic photographs were taken Are macroscopic photographs available? Yes;No Yes;No Alphanumeric

If YES is answered explain what macroscopic photographs were taken

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C15075 Brain atrophy cerebellum cortical neuronal loss in receptive layer indicator BrAtCerebCortNeurLossRecLayInd Indicator of cortical neuronal loss in the receptive layer (granular) of the cerebellum Indicator of cortical neuronal loss in the receptive layer (granular) of the cerebellum Receptive layer (granular) No, neuronal loss;Yes, neuronal loss No, neuronal loss;Yes, neuronal loss Alphanumeric

Cerebellum; Cortical neuronal loss

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C14983 Brain atrophy coronal sections amygdala status BrAtCorSecAmygdalaStat Status of amygdala atrophy of the coronal sections upon gross examination Status of amygdala atrophy of the coronal sections upon gross examinatio Amygdala atrophy Absent;Present Absent;Present Alphanumeric

Coronal slices: On gross examination of the coronal sections

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C17756 Striatum atrophy claustrum atrophy severity result StrAtrophyClauAtrophySevReslt Quantitative result of the severity of atrophy located in the claustrum Quantitative result of the severity of atrophy located in the claustr Present Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

Striatum atrophy

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C17765 Striatum atrophy hydrocephalus lateral ventricle severity result StrAtrophyHydroLatVentSevReslt Quantitative result of the severity of hydrocephalus located in the lateral ventricle Quantitative result of the severity of hydrocephalus located in the lateral ventricl Lateral ventricle None;Mild;Moderate;Severe;Not assessed;Not available None;Mild;Moderate;Severe;Not assessed;Not available Alphanumeric

Striatum atrophy; Hydrocephalus

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C15054 Brain atrophy substantia nirgra pars compacta neuronal loss severity result BrAtSubNiParsCoNeuLossSevReslt Quantitative result of the severity of neuronal loss in the pars compacta Quantitative result of the severity of neuronal loss in the pars compact Yes, neuronal loss Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

Substantia nigra

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C08173 Ischemic hemorrhagic or vascular pathology indicator IschHemVasclPathInd Indicator of the presence of ischemic, hemorrhagic, or vascular pathology Indicator of the presence of ischemic, hemorrhagic, or vascular pathology Are there ischemic or hemorrhagic changes? Yes;No;Unknown;Not assessed Yes;No;Unknown;Not assessed Alphanumeric

If 'No' is answered for ischemic or hemorrhagic changes, skip to question 43.

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C15086 Ischemic or hemorrhagic changes event category IschHemChangesEventCat Category of the ischemic or hemorrhagic changes Category of the ischemic or hemorrhagic changes Yes, present Single;Multiple Single;Multiple Alphanumeric

No additional instructions

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C15022 Brain atrophy nucleus coeruleus appearance grade BrAtNucleusCoeruleusAppGrade Grade of pigmentation of the nucleus coeruleus Grade of pigmentation of the nucleus coeruleus Nucleus coeruleus Well pigmented;Darker 1+;Darker 2+;Darker 3+;Very severe 4+ (Darker);Paler 1+;Paler 2+;Paler 3+;Very severe 4+ (Paler) Well pigmented;Darker 1+;Darker 2+;Darker 3+;Very severe 4+ (Darker);Paler 1+;Paler 2+;Paler 3+;Very severe 4+ (Paler) Alphanumeric

Striatum atrophy

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C15033 Brain atrophy amygdala neuronal loss indicator BrAtAmygdalaNeurLossInd Indicator of neuronal loss in the amygdala Indicator of neuronal loss in the amygdal Amygdala Neuronal Loss No neuronal loss;Yes neuronal loss No neuronal loss;Yes neuronal loss Alphanumeric

No additional instructions

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C06005 Data collected date and time DataCollDateTime Date (and time, if applicable and known) the data were collected. This may be the date/time a particular examination or procedure was performed Date (and time, if applicable and known) the data were collected. This may be the date/time a particular examination or procedure was performe Date form completed Date or Date & Time

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

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Free-Form Entry

C18996 Silver staining methods other text SilverStainMethdsOTH The free-text field related to 'Silver staining methods type' specifying other text. Silver staining methods used for identifying Alzheimer disease type changes The free-text field related to 'Silver staining methods type' specifying other text. Silver staining methods used for identifying Alzheimer disease type changes Other, specify Alphanumeric

Answer for each type of microscopic brain abnormality

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Free-Form Entry

C15065 Brain atrophy pons neuronal loss indicator BrAtPonsNeurLossInd Indicator of neuronal loss in the pons Indicator of neuronal loss in the pon Pons Neuronal loss No neuronal loss;Yes neuronal loss No neuronal loss;Yes neuronal loss Alphanumeric

Pons: Neuronal loss

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C14973 Microscopical examination blocks source MicroExamBlocksSource The source of blockage based on microscopical examination of brain The source of blockage based on microscopical examination of brain Microscopical examination Source of blocks Not available;Other, specify;Bilateral;Left half of brain;Right half of brain Not available;Other, specify;Bilateral;Left half of brain;Right half of brain Alphanumeric

Indicate the parts selected for evaluation

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C15097 Single or multiple hemorrhages description text SingMultiHemDescriptTxt The text description of the hemorrhages The text description of the hemorrhages Describe Alphanumeric

Answer for each vascular territory and event category

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Free-Form Entry

C15108 Diagnoses final clinicopathological severity scale DiagnosFinClinicopathSevScale Scale of the severity or intensity of the diagnosis Scale of the severity or intensity of the diagnosis Final Clinicopathological Diagnosis Mild;Moderate;Severe Mild;Moderate;Severe Alphanumeric

Only answered if "Encephalopathy of hypoxic-ischemic type, acute", "Alzheimer changes", or "Status cribrosus and lacunaris" are answered for Final Clinicopathological diagnoses

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C15044 Brain atrophy thalamus neuronal loss severity result BrAtThalamusNeurLossSevReslt Quantitative result of the severity of neuronal loss in the thalamus Quantitative result of the severity of neuronal loss in the thalamus Yes, neuronal loss Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

This question is answered if "Yes, neuronal loss" is answered for 'Thalamus: neuronal loss"

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C08158 Brain weight measurement BrainWgtMeasr Weight of the participant's/subject's brain in grams Weight of the participant's/subject's brain in grams Brain weight-Part weighed Numeric Values

This value should be recorded in grams (g) for all brain tissue weighed

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gram
C15076 Brain atrophy cerebellum cortical neuronal loss in receptive layer severity result BrAtCerCortNeuLosRecLaSevReslt Quantitative result of the severity of cortical neuronal loss in the receptive layer of the cerebellum Quantitative result of the severity of cortical neuronal loss in the receptive layer of the cerebellum Yes, neuronal loss Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ Alphanumeric

Cerebellum; Cortical neuronal loss

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C14984 Brain atrophy coronal sections amygdala severity result BrAtCorSecAmygdalaSevReslt Quantitative result of the severity of amygdala atrophy in the coronal sections of the brain Quantitative result of the severity of amygdala atrophy in the coronal sections of the brain Present Mild 1+;Moderate 2+;Severe3+;Very severe 4+ Mild 1+;Moderate 2+;Severe3+;Very severe 4+ Alphanumeric

Coronal slices: On gross examination of the coronal sections

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CSV