CDE Detailed Report

Disease: Mitochondrial Disease
Subdomain Name: Exercise Physiology
CRF: Staged Exercise Tolerance Test

Displaying 151 - 192 of 192
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C59908 Tidal volume body temperature pressure saturate submaximal absolute trial complete oxygen uptake peak ratio value VtBTPSSubATCmpltVO2PeakRatVal Value, as a percentage, of the ratio of the body temperature, pressure, saturated tidal volume ((in liters) (Vt BTPS (L)) during the Submaximal Absolute Trial to the Vt BTPS (L) at the time oxygen uptake (VO2) peaked Value, as a percentage, of the ratio of the body temperature, pressure, saturated tidal volume ((in liters) (Vt BTPS (L)) during the Submaximal Absolute Trial to the Vt BTPS (L) at the time oxygen uptake (VO2) peaked. Vt BTPS (L): AT / VO2 Peak (%) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:06.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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percent
C60004 Gas exhale volume trial start measurement VETrialStartMeasr Measurement of the volume of gas exhaled (VE) at the beginning of the exercise trial Measurement of the volume of gas exhaled (VE) at the beginning of the exercise trial Start Ex: VE Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:31.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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C60051 Perceived exertion trial recovery start Borg scale PrcvdExrtnTrlRcvryStrtBrgScale Scale value of perceived exertion (PE) using the Borg Scale at the beginning of the trial recovery period Scale value of perceived exertion (PE) using the Borg Scale at the beginning of the trial recovery period Start R: Borg PE Numeric Values

Borg scale - The scale is mainly validated in older healthy children and adults, but the clinician can determine if administration is appropriate based on the participant's cognitive ability to understand the scale

No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:47:08.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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C59940 Respiratory exchange ratio submaximal absolute trial complete oxygen uptake peak ratio value RERSubATCmpltVO2PeakRatVal Value, as a percentage, of the ratio of the Respiratory Exchange Ratio (RER) (the ratio of carbon dioxide output, VCO2, to oxygen uptake, VO2) during the Submaximal Absolute Trial to the RER at the attainment of peak VO2 Value, as a percentage, of the ratio of the Respiratory Exchange Ratio (RER) (the ratio of carbon dioxide output, VCO2, to oxygen uptake, VO2) during the Submaximal Absolute Trial to the RER at the attainment of peak VO2. RER: AT / VO2 Peak (%) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:36.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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percent
C56213 Rest carbon dioxide output measurement RestVCO2Measr Measurement, in milliliters per minute (mL/min), of carbon dioxide output (VCO2) at rest Measurement, in milliliters per minute (mL/min), of carbon dioxide output (VCO2) at rest VCO2 (mL/min): Rest Numeric Values Adult;Pediatric Supplemental-Highly Recommended 1.10 2024-02-29 15:45:27.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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milliliter per minute
C57113 Start recovery time StrtRcvryTime Time of the start of recovery Time of the start of recovery Start Recovery Date or Date & Time Adult;Pediatric Supplemental-Highly Recommended 1.00 2017-12-28 12:19:10.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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C59983 Rate pressure product ventilatory absolute threshold value RatePrsPdVATVal Value of the Rate Pressure Product at the attainment of the ventilatory anaerobic threshold (VAT), calculated as the product of the systolic blood pressure (in millimeters of mercury, mmHg) multiplied by the heart rate (in beats per minute, BPM), which quantity is then divided by 100 Value of the Rate Pressure Product at the attainment of the ventilatory anaerobic threshold (VAT), calculated as the product of the systolic blood pressure (in millimeters of mercury, mmHg) multiplied by the heart rate (in beats per minute, BPM), which qu RatePrsPd SBP*HR/100: VAT (optional) Numeric Values

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C60030 Respiratory exchange ratio submaximal absolute trial end value RERSubATEndVal Value of the Respiratory Exchange Ratio (RER) (the ratio of carbon dioxide output, VCO2, to oxygen uptake, VO2) at the conclusion of the Submaximal Absolute Trial Value of the Respiratory Exchange Ratio (RER) (the ratio of carbon dioxide output, VCO2, to oxygen uptake, VO2) at the conclusion of the Submaximal Absolute Trial AT: RER Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:52.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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C59919 Oxygen uptake submaximal absolute trial unit mass measurement VO2SubATUnitMassMeasr Measurement, in milliliters per kilogram per minute (mL/kg/min), of oxygen uptake (VO2) during the Submaximal Absolute Trial Measurement, in milliliters per kilogram per minute (mL/kg/min), of oxygen uptake (VO2) during the Submaximal Absolute Trial VO2 (mL/kg/min): Submaximal (15 Watts x 5 min) Absolute Trial Numeric Values

No instructions available

No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:17.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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milliliter per kilogram per minute
C60015 Carbon dioxide trial other timepoint measurement VCO2TrialOthTmptMeasr Measurement, in milliliters per minute (mL/min), of carbon dioxide output (VCO2) at the specified timepoint during the exercise trial Measurement, in milliliters per minute (mL/min), of carbon dioxide output (VCO2) at the specified timepoint during the exercise trial Other Timepoint: VCO2 (mL/min) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:40.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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milliliter per minute
C59951 Oxygen uptake heart rate submaximal absolute trial complete oxygen uptake peak ratio value VO2HRSubATCompltVO2PeakRatVal Value, as a percentage, of the ratio of (1) the ratio of oxygen uptake (VO2), in milliliters (mL), to the heart rate, in beats per minute (BPM), during the Submaximal Absolute Trial to (2) the same ratio at the attainment of peak VO2 Value, as a percentage, of the ratio of (1) the ratio of oxygen uptake (VO2), in milliliters (mL), to the heart rate, in beats per minute (BPM), during the Submaximal Absolute Trial to (2) the same ratio at the attainment of peak VO2. VO2/HR (mL/beat): AT / VO2 Peak (%) Numeric Values

No instructions available

No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:46.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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percent
C59962 Oxygen ventilatory equivalent oxygen uptake peak predict value VEVO2VO2PeakPredctVal Value of the predicted ratio of the volume of gas exhaled (VE) to oxygen uptake (VO2) when peak VO2 was attained Value of the predicted ratio of the volume of gas exhaled (VE) to oxygen uptake (VO2) when peak VO2 was attained VE/VO2: Prediction Numeric Values

Prediction - Prediction formula used to be determined by the study

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C59898 Work oxygen uptake peak predict value WorkVO2PkPrdctVal Value predicted for instantaneous work, in watts, at attainment of peak oxygen uptake (VO2) Value predicted for instantaneous work, in watts, at attainment of peak oxygen uptake (VO2) Work (Watts): Prediction Numeric Values

Prediction - Prediction formula used to be determined by the study

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watt
C59994 Leg fatigue submaximal absolute trial Borg scale LegFatigSubATBorgScale Scale value of leg fatigue during the Submaximal Absolute Trial using the Borg Scale Scale value of leg fatigue during the Submaximal Absolute Trial using the Borg Scale Borg - legs: Submaximal (15 Watts x 5 min) Absolute Trial Numeric Values

Borg scale - The scale is mainly validated in older healthy children and adults, but the clinician can determine if administration is appropriate based on the participant's cognitive ability to understand the scale

No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:23.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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C60041 Oxygen uptake unit mass trial recovery start measurement VO2UnitMassTrRcvryStartMeasr Measurement, in milliliters per kilogram per minute (mL/kg/min), of oxygen uptake (VO2) at the beginning of the trial recovery period Measurement, in milliliters per kilogram per minute (mL/kg/min), of oxygen uptake (VO2) at the beginning of the trial recovery period Start R: VO2 (mL/kg/min) Numeric Values

No instructions available

No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:47:01.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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milliliter per kilogram per minute
C59930 Oxygen uptake peak measure predict ratio value VO2PkMeasrPredctRatVal Value, as a percentage, of the ratio at peak oxygen uptake (VO2) of measured peak VO2 to predicted peak VO2 Value, as a percentage, of the ratio at peak oxygen uptake (VO2) of measured peak VO2 to predicted peak VO2 VO2 (mL/min): VO2 Peak/Prediction (%) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:27.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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percent
C60026 Work submaximal absolute trial end measurement WordSubATEndMeasr Measurement of work, in watts, generated at the conclusion of the Submaximal Absolute Trial Measurement of work, in watts, generated at the conclusion of the Submaximal Absolute Trial AT: Work (watts) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:49.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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watt
C56219 Rest respiratory exchange ratio value RestRERVal Value of the Respiratory Exchange Ratio (RER) (the ratio of carbon dioxide output, VCO2, to oxygen uptake, VO2) at rest Value of the Respiratory Exchange Ratio (RER) (the ratio of carbon dioxide output, VCO2, to oxygen uptake, VO2) at rest RER: Rest Numeric Values Adult;Pediatric Supplemental-Highly Recommended 1.10 2024-02-29 15:45:33.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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C59973 Blood pressure systolic submaximal absolute trial measurement BPSysSubATMeasr Measurement, in millimeters of mercury (mmHg), of systolic blood pressure (BP) during the Submaximal Absolute Trial Measurement, in millimeters of mercury (mmHg), of systolic blood pressure (BP) during the Submaximal Absolute Trial sysBP (mmHg): Submaximal (15 Watts x 5 min) Absolute Trial Numeric Values

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millimeter of mercury
C59909 Respiration submaximal absolute trial rate RespSubATrRate Rate of respiration (RR), in breaths per minute, during the Submaximal Absolute Trial Rate of respiration (RR), in breaths per minute, during the Submaximal Absolute Trial RR (br/min): Submaximal (15 Watts x 5 min) Absolute Trial Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:07.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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breath per minute
C60005 Tidal volume body temperature pressure saturate trial start measurement VtBTPSTrialStartMeasr Measurement, in liters per minute (L/min), of body temperature, pressure, saturated tidal volume (Vt BTPS) at the beginning of the exercise trial Measurement, in liters per minute (L/min), of body temperature, pressure, saturated tidal volume (Vt BTPS) at the beginning of the exercise trial Start Ex: BTPS (L/min) Numeric Values

No instructions available

No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:32.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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liter per minute
C60052 Exercise test date ExerciseTestDate Date on which the exercise test was performed Date on which the exercise test was performed Date of Exercise Tests Date or Date & Time

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C59941 Heart rate submaximal absolute trial measurement HRSubATMeasr Measurement, in beats per minute (BPM), of the heart rate during the Submaximal Absolute Trial Measurement, in beats per minute (BPM), of the heart rate during the Submaximal Absolute Trial Heart Rate (BPM): Submaximal (15 Watts x 5 min) Absolute Trial Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:37.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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beat per minute
C57114 Rest time count RstTime Count of the time (in minutes) taken at rest Count of the time (in minutes) taken at rest Time (min): Rest Numeric Values Adult;Pediatric Supplemental-Highly Recommended 3.00 2024-03-18 15:27:50.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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minute
C59984 Rate pressure product oxygen uptake peak measure value RatePrsPdVO2PeakMeasrVal Measured value of the Rate Pressure Product at the attainment of peak oxygen uptake (VO2), calculated as the product of the systolic blood pressure (in millimeters of mercury, mmHg) multiplied by the heart rate (in beats per minute, BPM), which quantity is then divided by 100 Measured value of the Rate Pressure Product at the attainment of peak oxygen uptake (VO2), calculated as the product of the systolic blood pressure (in millimeters of mercury, mmHg) multiplied by the heart rate (in beats per minute, BPM), which quantity i RatePrsPd SBP*HR/100: VO2 Peak Numeric Values

V02 Peak - If participant cannot complete submaximal test, indicate time at exhaustion and record as VO2 Peak

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C60031 Heart submaximal absolute trial end rate HeartSubATEndRate Heart rate, in beats per minute (BPM), at the conclusion of the Submaximal Absolute Trial Heart rate, in beats per minute (BPM), at the conclusion of the Submaximal Absolute Trial AT: Heart Rate (BPM) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:53.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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beat per minute
C59920 Oxygen uptake ventilatory anaerobic threshold unit mass measurement VO2VATUnitMassMeasr Measurement, in milliliters per kilogram per minute (mL/kg/min), of oxygen uptake (VO2) when the ventilatory anaerobic threshold (VAT) was attained Measurement, in milliliters per kilogram per minute (mL/kg/min), of oxygen uptake (VO2) when the ventilatory anaerobic threshold (VAT) was attained VO2 (mL/kg/min): VAT (optional) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:18.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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milliliter per kilogram per minute
C60016 Respiratory exchange ratio trial other timepoint value RERTrialOthTmptVal Value of the Respiratory Exchange Ratio (RER) (the ratio of carbon dioxide output, VCO2, to oxygen uptake, VO2) at the specified timepoint during the exercise trial Value of the Respiratory Exchange Ratio (RER) (the ratio of carbon dioxide output, VCO2, to oxygen uptake, VO2) at the specified timepoint during the exercise trial Other Timepoint: RER Numeric Values

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C59952 Oxygen uptake heart rate oxygen uptake peak measure predict ratio value VO2HRVO2PeakMeasrPredctRatVal Value, as a percentage, of the ratio at peak oxygen uptake (VO2) of (1) the measured ratio of VO2, in milliliters (mL), to the heart rate, in beats per minute (BPM), to (2) the predicted ratio of VO2 to the heart rate Value, as a percentage, of the ratio at peak oxygen uptake (VO2) of (1) the measured ratio of VO2, in milliliters (mL), to the heart rate, in beats per minute (BPM), to (2) the predicted ratio of VO2 to the heart rate VO2/HR (mL/beat): VO2 Peak/Prediction (%) Numeric Values

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percent
C59963 Oxygen ventilatory equivalent submaximal absolute trial complete oxygen uptake peak ratio value VEVO2SubATCmpltVO2PeakRatVal Value, as a percentage, of the ratio of (1) the ratio of the volume of gas exhaled (VE) to oxygen uptake (VO2) during the Submaximal Absolute Trial to (2) the same ratio at the attainment of peak VO2 Value, as a percentage, of the ratio of (1) the ratio of the volume of gas exhaled (VE) to oxygen uptake (VO2) during the Submaximal Absolute Trial to (2) the same ratio at the attainment of peak VO2 VE/VO2: AT / VO2 Peak (%) Numeric Values

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percent
C59899 Work submaximal absolute trial complete oxygen uptake peak ratio value WorkSubATCmpltVO2PkRatVal Value, as a percentage, of the ratio of the work (in watts) generated during the Submaximal Absolute Trial to the instantaneous work (in watts) being generated at the time oxygen uptake (VO2) peaked Value, as a percentage, of the ratio of the work (in watts) generated during the Submaximal Absolute Trial to the instantaneous work (in watts) being generated at the time oxygen uptake (VO2) peaked. Work (Watts): AT / VO2 Peak (%) Numeric Values

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percent
C59995 Leg fatigue ventilatory anaerobic threshold Borg scale LegFatigVATBorgScale Scale value of leg fatigue using the Borg Scale when the ventilatory anaerobic threshold (VAT) was attained Scale value of leg fatigue using the Borg Scale when the ventilatory anaerobic threshold (VAT) was attained Borg - legs: VAT (optional) Numeric Values

Borg scale - The scale is mainly validated in older healthy children and adults, but the clinician can determine if administration is appropriate based on the participant's cognitive ability to understand the scale

No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:24.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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C60042 Carbon dioxide trial recovery start measurement VCO2TrialRecoveryStartMeasr Measurement, in milliliters per minute (mL/min), of carbon dioxide output (VCO2) at the beginning of the trial recovery period Measurement, in milliliters per minute (mL/min), of carbon dioxide output (VCO2) at the beginning of the trial recovery period Start R: VCO2 (mL/min) Numeric Values

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milliliter per minute
C59931 Carbon dioxide output submaximal absolute trial measurement VCO2SubATMeasr Measurement, in milliliters per minute (mL/min), of carbon dioxide output (VCO2) during the Submaximal Absolute Trial Measurement, in milliliters per minute (mL/min), of carbon dioxide output (VCO2) during the Submaximal Absolute Trial VCO2 (mL/min): Submaximal (15 Watts x 5 min) Absolute Trial Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:28.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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milliliter per minute
C60027 Oxygen uptake submaximal absolute trial end measurement VO2SubATEndMeasr Measurement, in milliliters per minute (mL/min), of oxygen uptake (VO2) at the conclusion of the Submaximal Absolute Trial Measurement, in milliliters per minute (mL/min), of oxygen uptake (VO2) at the conclusion of the Submaximal Absolute Trial AT: VO2 (mL/min) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:50.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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milliliter per minute
C56161 Pre test comment text PreTestCommentTxt The free-text field representing any comments before the test The free-text field representing any comments before the test Pre Test Comments Alphanumeric Adult;Pediatric Supplemental-Highly Recommended 1.10 2024-02-29 15:44:17.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations 255

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C56225 Rest heart rate measurement RestHRMeasr Measurement, in beats per minute (BPM), of the heart rate at rest Measurement, in beats per minute (BPM), of the heart rate at rest Heart Rate (BPM): Rest Numeric Values Adult;Pediatric Supplemental-Highly Recommended 1.10 2024-02-29 15:45:36.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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beat per minute
C59974 Blood pressure systolic ventilatory anaerobic threshold measurement BPSysVATMeasr Measurement, in millimeters of mercury (mmHg), of systolic blood pressure (BP) when the ventilatory anaerobic threshold (VAT) was attained Measurement, in millimeters of mercury (mmHg), of systolic blood pressure (BP) when the ventilatory anaerobic threshold (VAT) was attained sysBP (mmHg): VAT (optional) Numeric Values

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millimeter of mercury
C59910 Respiration ventilatory anaerobic threshold rate RespVATRate Rate of respiration (RR), in breaths per minute, when the ventilatory anaerobic threshold (VAT) was attained Rate of respiration (RR), in breaths per minute, when the ventilatory anaerobic threshold (VAT) was attained RR (br/min): VAT (optional) Numeric Values

No instructions available

No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:08.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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breath per minute
C60006 Respiration rate trial start measurement RRTrialStartMeasr Measurement, in breaths per minute (br/min), of the respiratory rate at the beginning of the exercise trial Measurement, in breaths per minute (br/min), of the respiratory rate at the beginning of the exercise trial Start Ex: RR (br/min) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:46:33.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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breath per minute
C60053 Participant subjective status trial 1 end text PtcptSbjctvStatusTrial1EndText The free-text field capturing the participant's description of how they felt at the conclusion of the first exercise trial The free-text field capturing the participant's description of how they felt at the conclusion of the first exercise trial How did you feel following the first exercise test? Alphanumeric

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C59942 Heart rate ventilatory anaerobic threshold measurement HRVATMeasr Measurement, in beats per minute (BPM), of the heart rate when the ventilatory anaerobic threshold (VAT) was attained Measurement, in beats per minute (BPM), of the heart rate when the ventilatory anaerobic threshold (VAT) was attained Heart Rate (BPM): VAT (optional) Numeric Values

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No references available Adult;Pediatric Supplemental-Highly Recommended 1.00 2024-02-29 15:45:38.0 Staged Exercise Tolerance Test Exercise Physiology Assessments and Examinations

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beat per minute
CSV