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Functional Impairment Scale
Please see the following link: Funtional Impairment Scale (FIS) (refer to Section 1.3.11).
Supplemental: Headache
Short Description of Instrument
The Functional Impairment Scale (FIS) is a four (4) point scale, single global item. FIS addresses functional status and intensity of impairment during daily activities. Functional disability status should be recorded by the participant before medication intake.
The four point FIS scale is as follows:
3 = severe impairment during performance of daily activity
2 = moderate impairment during performance of daily activity
1 = mild impairment during performance of daily activity
            0 = normal level of functioning; no disability
Silberstein SD, Cady RK, Sheftell FD, Almas M, Parsons B, Albert KS. Efficacy of Eletriptan in Migraine-Related Functional Impairment: Functional and Work Productivity Outcomes. Headache. 2007;47(5):673-682.
Tfelt-Hansen P, Block G, DahlÖf C, Diener HC, Ferrari MD, Goadsby PJ, Guidetti V, Jones B, Lipton RB, Massiou H, Meinert C, Sandrini G, Steiner T, Winter PB; International Headache Society Clinical Trials Subcommittee. Guidelines for controlled trials of drugs in migraine: second edition. Cephalalgia.


Document last updated February 2018