CDE Detailed Report

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CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C13230 Modified Rankin Scale (mRS) Score MRSScore The overall modified Rankin Scale (mRS) score assigned to the participant/ subject The overall modified Rankin Scale (mRS) score assigned to the participant/ subject Modified Rankin Scale score (mRS) 0;1;2;3;4;5;6 No symptoms at all;No significant disability despite symptoms, able to carry out all usual duties and activities;Slight disability, unable to carry out all previous activities, but able to look after own affairs without assistance;Moderate disability, requiring some help, but able to walk without assistance;Moderately severe disability, unable to walk without assistance and unable to attend to own bodily needs without assistance;Severe disability, bedridden, incontinent and requiring constant nursing care and attention;Dead Numeric values Adult;Pediatric Exploratory 3.00 2013-06-21 00:00:00.0 Disability-Adjusted Life Years (DALY) [php] [php_1]

Single Pre-Defined Value Selected

C111520
C54722 Death age value DeathAgeVal Value of the subject/participant's age at death Value of the subject/participant's age at death Age at death (years) Numeric Values Adult;Pediatric Exploratory 1.00 2017-04-10 16:08:18.0 Disability-Adjusted Life Years (DALY) [php] [php_1]

Free-Form Entry

0 130
C54723 Disability elapsed year count DisabilityElapsYearCt Count of elapsed years that the subject/participant jas had the specified disability Count of elapsed years that the subject/participant jas had the specified disability Years with disability Numeric Values Adult;Pediatric Exploratory 1.00 2017-04-10 16:10:14.0 Disability-Adjusted Life Years (DALY) [php] [php_1]

Free-Form Entry

0 130 years
C54724 Disability adjusted life year score DALYScore Disability-Adjusted Life Year (DALY) score Disability-Adjusted Life Year (DALY) score Disability-Adjusted Life Year (DALY) score (sum of Years of Life Lost [YLL] and the Years of Life Lost due to Disability [YLD]) Numeric Values

• DALY is the sum of Years of Life Lost (YLL) and the Years Lost due to Disability (YLD) ? DALY = YLL + YLD • The YLL is the number of deaths multiplied by the standard life expectancy at the age of death: ? YLL = N x L ? N = number of deaths ? L = standard life expectancy at age of death (years) • The YLD is calculated using the number of incident cases in a time period, the average duration of the disease and a disability weight factor: ? YLD = I x DW x L ? I = number of incident cases ? DW = disability weight ? L = average duration of the disease until remission or death (in years). • Please note that there is currently no defined disability weight for SAH. It can be calculated using the methodology in the publication Hong KS, Saver JL, Kang DW, Bae HJ, Yu KH, Koo J, Han MK, Cho YJ, Park JM, Lee BC. Years of optimum health lost due to complications after acute ischemic stroke: disability-adjusted life-years analysis. Stroke. 2010 Aug;41(8):1758-65. • For more information, visit http://www.who.int/healthinfo/global_burden_disease/metrics_daly/en/

Adult;Pediatric Exploratory 1.00 2017-04-10 16:14:01.0 Disability-Adjusted Life Years (DALY) [php] [php_1]

Free-Form Entry

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