CDE Detailed Report
Disease: Huntington's Disease
Subdomain Name: Other Clinical Data
CRF: Neuropathology Data Form
Displaying 151 - 175 of 175
Subdomain Name: Other Clinical Data
CRF: Neuropathology Data Form
Displaying 151 - 175 of 175
| CDE ID | CDE Name | Variable Name | Definition | Short Description | Question Text | Permissible Values | Description | Data Type | Disease Specific Instructions | Disease Specific Reference | Population | Classification (e.g., Core) | Version Number | Version Date | CRF Name (CRF Module / Guidance) | Subdomain Name | Domain Name | Size | Input Restrictions | Min Value | Max Value | Measurement Type | External Id Loinc | External Id Snomed | External Id caDSR | External Id CDISC |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| C15026 | Brain atrophy cerebellum severity result | BrAtCerebellumSevReslt | Quantitative result of the severity of cerebellum atrophy located in the striatum | Quantitative result of the severity of cerebellum atrophy located in the striatu | Present | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
This question is answered if 'Present' is answered for 'Cerebellum atrophy' |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17760 | Striatum atrophy thalamus atrophy severity result | StrAtrophyThalAtrophySevReslt | Quantitative result of the severity of atrophy located in the thalamus | Quantitative result of the severity of atrophy located in the thalam | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15058 | Brain atrophy substantia nigra Lewy body containing neurons and Lewy neurites severity result | BrAtSubNigraLeCBodLeNeSevReslt | Quantitative result of the severity of lewy-body containing neurons (LBCN) and lewy neurites (LN) in the substantia nigra. | Quantitative result of the severity of Lewy-body containing neurons (LBCN) and Lewy neurites (LN) in the substantia nigra. | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Substantia nigra |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08179 | Cortical laminar necrosis indicator | CortclLamnrNecrsisInd | Indicator of the presence of selective cortical necrosis of middle and lower cortical lamina most often associated with cerebral hypoperfusion and concentrated in border zones between major cerebral arteries | Indicator of the presence of selective cortical necrosis of middle and lower cortical lamina most often associated with cerebral hypoperfusion and concentrated in border zones between major cerebral arteries | Is there cortical laminar necrosis? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14977 | Brain atrophy coronal sections cerebral cortex status | BrainAtrophyCorSecCerCortStat | Status of cerebral cortex atrophy of the coronal sections upon gross examination | Status of cerebral cortex atrophy of the coronal sections upon gross examination | Cerebral cortex atrophy | Absent;Present | Absent;Present | Alphanumeric |
Coronal slices: On gross examination of the coronal sections |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15101 | Atherosclerotic vascular pathology indicator | AtheroscleroticVasclPathInd | Indicator of atherosclerotic, either non-stenotic or stenotic vascular changes (of the circle of Willis) | Indicator of atherosclerotic, either non-stenotic or stenotic vascular changes (of the circle of Willis) | Are there atherosclerotic, either non-stentoic or stentoic vascular changes? | None;Yes non-stenotic;Yes stenotic;Not assessed;Not available | None;Yes non-stenotic;Yes stenotic;Not assessed;Not available | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15037 | Brain atrophy neuronal loss and fibrillary astrocytosis putamen anatomic site | BrAtNeLosFibAstroPutAntmicSite | Anatomic site in the putamen where neuronal loss and/or fibrillary astrocytosis is/are present | Anatomic site in the putamen where neuronal loss and/or fibrillary astrocytosis is/are present | Putamen | Rostral, dorsal half;Rostral, ventral half;Nucleus accumbens | Rostral, dorsal half;Rostral, ventral half;Nucleus accumbens | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08151 | Diagnosis final clinical death date | DiagnosFinalClinDeathDate | Date of participant's/subject's final clinical diagnosis | Date of participant's/subject's final clinical diagnosis | Date of final clinical diagnosis | Date or Date & Time |
Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.). |
ISO 8601 - http://www.iso.org/iso/iso_catalogue.htm | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Free-Form Entry |
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| C15069 | Brain atrophy medulla oblongata dorsal nucleus vagus reticular formation status | BrAtMedObDorsNucVagRetFormStat | Status of dorsal nucleus of vagus reticular formation: Lewy body containing neurons (LBCN) and Lewy neurites (LN) in the medulla oblongata | Status of dorsal nucleus of vagus reticular formation: Lewy body containing neurons (LBCN) and Lewy neurites (LN) in the medulla oblongat | Dorsal nucleus of vagus - reticular formation Lewy body-containing neurons (LBCN) and Lewy neurites (LN) | Absent;Present | Absent;Present | Alphanumeric |
Medulla oblongata |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14988 | Brain atrophy striatum putamen severity result | BrAtStPutSevReslt | Quantitative result of the severity of atrophy located in the putamen | Quantitative result of the severity of atrophy located in the putame | Putamen | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe3+;Very severe 4+ | Alphanumeric |
Striatum atrophy: Atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C18667 | Data source other text | DataSourcOTH | The free-text field related to 'Data source' specifying other text. Source of the data provided on the case report form | The free-text field related to 'Data source' specifying other text. Source of the data provided on the case report form | Other, specify | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 1.00 | 2014-05-27 13:34:46.0 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 4000 |
Free-Form Entry |
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| C17398 | Specimen other postmortem text | SpecOthPostmortText | Text area to describe other banked postmortem specimens (e.g., blood, spinal cord, nerve, muscle) exist | Description of other available banked postmortem specimens | Yes (Describe) | Alphanumeric | No references available | Adult;Pediatric | Supplemental | 1.00 | 2012-12-20 00:00:00.0 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C15048 | Brain atrophy subthalamic nucleus neuronal loss severity result | BrAtSubthalNucNeurLossSevReslt | Quantitative result of the severity of neuronal loss in the subthalamic nucleus | Quantitative result of the severity of neuronal loss in the subthalamic nucleus | Yes, neuronal loss | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
This question is answered if "Yes, neuronal loss" is answered for 'Subthalamic nucleus: neuronal loss" |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08166 | Brain atrophy Braak and Braak neurofibrillary stage | BrAtBraakBraakNeurofibStage | Stages I and II correspond to NFT limited to the transentorhinal/entorhinal region; Stages III and IV to limbic stages; and Stages V and VI to neocortical stages. Stage VI implies involvement of primary cortices | Stages I and II correspond to NFT limited to the transentorhinal/entorhinal region; Stages III and IV to limbic stages; and Stages V and VI to neocortical stages. Stage VI implies involvement of primary cortice | If yes, select Braak stage | Stage I;Stage II;Stage III;Stage IV;Stage V;Stage VI | Stage I;Stage II;Stage III;Stage IV;Stage V;Stage VI | Alphanumeric |
This question is answered only if Present is answered for "Braak and Braak Neurofibrillary Tanlge Stage" |
No references available | Adult | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15080 | Brain atrophy cerebellum myelin loss in cerebellar white matter indicator | BrAtCerebMyeLossCerWMInd | Indicator of myelin loss in the cerebellar white matter of the cerebellum | Indicator of myelin loss in the cerebellar white matter of the cerebellum | Cerebellar white matter Myelin loss | No myelin loss;Yes myelin loss | No myelin loss;Yes myelin loss | Alphanumeric |
Cerebellum; Cerebellar white matter: Myelin loss |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15091 | Cortical infarcts single or multiple description text | CorInfarcSingMultiDescriptTxt | The text description of the cortical microinfarcts | The text description of the cortical microinfarcts | Describe | Alphanumeric |
Answer for each vascular territory and event category |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations | 255 |
Free-Form Entry |
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| C15027 | Brain atrophy cortex neuronal loss indicator | BrAtCerebralCortexNeurLossInd | Indicator of neuronal loss in the cerebral cortex | Indicator of neuronal loss in the cerebral cortex | Cerebral cortex Neuronal loss | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C17761 | Striatum atrophy subthalamic nucleus atrophy status | StrAtrophySubthalNuAtrophyStat | Status of atrophy in the subthalamic nucleus | Status of atrophy in the subthalamic nucleu | Thalamus atrophy | Absent;Present | Absent;Present | Alphanumeric |
Striatum atrophy |
No references available | Adult | Supplemental | 3.00 | 2013-08-30 17:06:52.8 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15059 | Brain atrophy nucleus coeruleus neuronal loss indicator | BrAtNucCoerNeurLossInd | Indicator of neuronal loss in the nucleus coeruleus | Indicator of neuronal loss in the nucleus coeruleu | Nucleus coeruleus | No neuronal loss;Yes neuronal loss | No neuronal loss;Yes neuronal loss | Alphanumeric |
Nucleus coeruleus |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08181 | Other pathology ischemic vascular disease indicator | OthrPathlgyIschmcVasclrDisInd | Indicator of the presence of another ischemic or vascular disease not specifically mentioned previously | Indicator of the presence of another ischemic or vascular disease not specifically mentioned previously | Are there other vascular-depending changes, which are not previously specified? | Yes, specify;No;Not assessed;Unknown | Yes, specify;No;Not assessed;Unknown | Alphanumeric |
If yes, specify other |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C14978 | Brain atrophy coronal sections cerebral cortex severity result | BrainAtCorSecCereCorSevReslt | Quantitative result of the severity of cerebral cortex atrophy in the coronal sections of the brain | Quantitative result of the severity of cerebral cortex atrophy in the coronal sections of the brain | Present | 0;1+/4+;2+/4+;3+/4+;4+/4+ | 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe | Alphanumeric |
Coronal slices: On gross examination of the coronal sections |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15102 | Arteriosclerosis indicator | ArteriosclerosisInd | Indicator of arteriosclerosis (small parenchymal arteriolar disease) | Indicator of arteriosclerosis (small parenchymal arteriolar disease) | Is there arteriosclerosis (small parenchymal arteriolar disease)? | Yes;No;Unknown;Not assessed | Yes;No;Unknown;Not assessed | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15038 | Brain atrophy neuronal loss nucleus accumbens severity result | BrAtNeurLossNucAccSevReslt | Quantitative result of the severity of neuronal loss in the nucleus accumbens | Quantitative result of the severity of neuronal loss in the nucleus accumbens | Nucleus accumbens | 0;1+/4+;2+/4+;3+/4+;4+/4+;NA | 0=None;1+/4+=Mild;2+/4+=Moderate;3+/4+=Severe;4+/4+=Very severe;NA=Not available | Alphanumeric |
No additional instructions |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C08152 | Brain tissue frozen indicator | BrainTissFrozenInd | Indicator of whether banked frozen brain tissue is accessible | Indicator of whether banked frozen brain tissue is accessible | Is banked frozen brain tissue available? | Yes;No | Yes;No | Alphanumeric |
No additional instructions |
No references available | Adult;Pediatric | Supplemental | 3.00 | 2013-07-22 09:34:41.527 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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| C15070 | Brain atrophy medulla oblongata dorsal nucleus of vagus reticular formation severity result | BrAtMedObDorNucVagRetFSevReslt | Quantitative result of the severity of dorsal nucleus of vagus reticular formation: LBCN and LN in the medulla oblongata | Quantitative result of the severity of dorsal nucleus of vagus reticular formation: LBCN and LN in the medulla oblongata | Present | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Mild 1+;Moderate 2+;Severe 3+;Very severe 4+ | Alphanumeric |
Medulla oblongata |
No references available | Adult | Supplemental | 3.00 | 2013-07-14 19:48:50.273 | Neuropathology Data Form | Other Clinical Data | Assessments and Examinations |
Single Pre-Defined Value Selected |
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