CDE Detailed Report

Disease: Stroke
Subdomain Name: Drugs
CRF: content

Displaying 1 - 21 of 21
CDE ID CDE Name Variable Name Definition Short Description Question Text Permissible Values Description Data Type Disease Specific Instructions Disease Specific Reference Population Classification (e.g., Core) Version Number Version Date CRF Name (CRF Module / Guidance) Subdomain Name Domain Name Size Input Restrictions Min Value Max Value Measurement Type External Id Loinc External Id Snomed External Id caDSR External Id CDISC
C58852 IV tPA not started MRI selection treatment beyond 4.5 hour reason IVtPANtStMRITrtSctByd4HlfHrRsn If NO Intravenous Tissue Plasminogen Activator (IV tPA) was initiated for the participant/subject treated using MRI imaging selection beyond 4.5 hours, documents reasons in the medical record for why no IV tPA was started for the participant/subject at your hospital. Were one or more of the following reasons for not administering IV thrombolytic therapy at this hospital explicitly documented by a physician, advance practice nurse, or physician assistant's notes in the medical record? If NO Intravenous Tissue Plasminogen Activator (IV tPA) was initiated for the participant/subject treated using MRI imaging selection beyond 4.5 hours, documents reasons in the medical record for why no IV tPA was started for the participant/subject at your hospital. Were one or more of the following reasons for not administering IV thrombolytic therapy at this hospital explicitly documented by a physician, advance practice nurse, or physician assistant's notes in the medical record Other reasons tPA is not started for patients treated using MRI imaging selection beyond 4.5 hours Treatment cannot be started within 4.5 hours of symptom recognition;Age > 80;Parenchymal hyperintensity visible on FLAIR;NIHSS > 25;CT findings of >1/3 MCA or >50% of ACA or PCA territories, or > 100ml;Any MRI findings indicative of a high risk of SICH Treatment cannot be started within 4.5 hours of symptom recognition;Age > 80;Parenchymal hyperintensity visible on FLAIR;NIHSS > 25;CT findings of >1/3 MCA or >50% of ACA or PCA territories, or > 100ml;Any MRI findings indicative of a high risk of SICH Alphanumeric

Choose all that apply.

No references available Adult;Pediatric Exploratory 1.00 2020-05-18 08:48:38.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Multiple Pre-Defined Values Selected

C58857 Angiographic image last date and time AngiographicImageLstDateTime Date (and time, if applicable and known) of last angiographic image for the participant/subject Date (and time, if applicable and known) of last angiographic image for the participant/subject Date and Time of last angiographic image or the end time for mechanical/pharmacologic intervention Date or Date & Time

If time of the last mechanical or pharmacological intervention not available, use the time on the last angiographic image.

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

No references available Adult;Pediatric Supplemental 1.00 2020-05-18 09:09:50.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

C14398 IV tissue plasminogen activator (tPA) total dose IVtPATtlDose Indicates the dose of IV tissue plasminogen activator (tPA) given to the participant/subject in mg Indicates the dose of IV tissue plasminogen activator (tPA) given to the participant/subject in mg Total IV tPA dose given Numeric Values

Record the numeric dose of tPA in mg.
It is important to consult these other data elements when calculating the IV tPA dose: Stroke Onset Time/ Time Patient Last Seen Well and Body Weight in kilograms.

No references available Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

0 300 milligram
C14409 Intra-sinus intervention groin puncture date and time IntrasinIntrvntGrnPuncDateTime Date (and time, if applicable and known) of groin puncture on the participant/ subject for intra-sinus intervention Date (and time, if applicable and known) of groin puncture on the participant/ subject for intra-sinus intervention Date and Time of groin puncture for intra-sinus procedure Date or Date & Time

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

No references available Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

C14399 IV tPA not started reason IVtPANotStartRsn If NO Intravenous Tissue Plasminogen Activator (IV tPA) was initiated, documents reasons in the medical record for why no IV tPA was started for the participant/subject at your hospital. Were one or more of the following reasons for not administering IV thrombolytic therapy at this hospital explicitly documented by a physician, advance practice nurse, or physician assistant's notes in the medical record? If NO Intravenous Tissue Plasminogen Activator (IV tPA) was initiated, documents reasons in the medical record for why no IV tPA was started for the participant/subject at your hospital. Were one or more of the following reasons for not administering IV thrombolytic therapy at this hospital explicitly documented by a physician, advance practice nurse, or physician assistant's notes in the medical record Reason(s) no IV tPA started at this hospital Active internal bleeding (<22 days);CT findings (ICH, SAH, or major infarct signs);History of intracranial hemorrhage or brain aneurysm or vascular malformation or brain tumor;Platelets <100,000, PTT> 40 sec after heparin use, or PT > 15 or INR > 1.7, or known bleeding diathesis;Recent intracranial or spinal surgery, head trauma, or stroke (<3 mo.);Recent surgery/trauma (<15 days);SBP > 185 or DBP > 110 mmHg despite treatment;Seizure at onset;Suspicion of subarachnoid hemorrhage;Subacute Bacterial Endocarditis (SBE);Advanced age;Care-team unable to determine eligibility;Glucose < 50 or > 400 mg/dl;Increased risk of bleeding due to Acute pericarditis, SBE, Hemostatic defects, Diabetic hemorrhagic retinopathy, Septic thrombophlebitis/occluded AV cannula, or currently receiving oral anticoagulants;IV or IA tPA given at outside hospital;Left heart thrombus;Life expectancy < 1 year or severe co-morbid illness or CMO on admission;Pregnancy;Patient/Family refused;Rapid improvement;Stroke severity - Too severe (e.g., NIHSS >22);Age > 80;Prior Stroke and Diabetes;Any anticoagulant use prior to admission (even if INR < 1.7);NIHSS > 25;CT findings of >1/3 MCA;Delay in Patient Arrival;Delay in Stroke diagnosis;In-hospital Time Delay;No IV access;Other, specify;Stroke severity nondisabling;MRI not feasible;CTP not feasible Active internal bleeding (<22 days);CT findings (ICH, SAH, or major infarct signs);History of intracranial hemorrhage or brain aneurysm or vascular malformation or brain tumor;Platelets <100,000, PTT> 40 sec after heparin use, or PT > 15 or INR > 1.7, or known bleeding diathesis;Recent intracranial or spinal surgery, head trauma, or stroke (<3 mo.);Recent surgery/trauma (<15 days);SBP > 185 or DBP > 110 mmHg despite treatment;Seizure at onset;Suspicion of subarachnoid hemorrhage;Subacute Bacterial Endocarditis (SBE);Advanced age;Care-team unable to determine eligibility;Glucose < 50 or > 400 mg/dl;Increased risk of bleeding due to Acute pericarditis, SBE, Hemostatic defects, Diabetic hemorrhagic retinopathy, Septic thrombophlebitis/occluded AV cannula, or currently receiving oral anticoagulants;IV or IA tPA given at outside hospital;Left heart thrombus;Life expectancy < 1 year or severe co-morbid illness or CMO on admission;Pregnancy;Patient/Family refused;Rapid improvement;Stroke severity - Too severe (e.g., NIHSS >22);Age > 80;Prior Stroke and Diabetes;Any anticoagulant use prior to admission (even if INR < 1.7);NIHSS > 25;CT findings of >1/3 MCA;Delay in Patient Arrival;Delay in Stroke diagnosis;In-hospital Time Delay;No IV access;Other, specify;Stroke severity nondisabling;MRI not feasible;CTP not feasible Alphanumeric

Choose all that apply.

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Multiple Pre-Defined Values Selected

C14410 Intra-sinus intervention initiated date and time IntrasinIntrvntInitiatDateTime Date (and time, if applicable and known) intra-sinus (IS) intervention (i.e., for cerebral venous thrombosis) was initiated at this hospital or ED Date (and time, if applicable and known) intra-sinus (IS) intervention (i.e., for cerebral venous thrombosis) was initiated at this hospital or ED Date and Time intra-sinus intervention initiated Date or Date & Time

The start time for IS therapy should be either the date and time on the angio showing evidence of treatment, or the start time of the infusion or mechanical deployment if the angio time is not available.

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

No references available Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

C14400 IV tPA at another hospital indicator IVtPAAnotherHospitalInd Indicates whether IV tPA was initiated for the participant/subject at an outside hospital Indicates whether IV tPA was initiated for the participant/subject at an outside hospital Was IV tPA initiated at an outside hospital Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one.

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Single Pre-Defined Value Selected

C14411 Investigational or experimental protocol for thrombolysis indicator InvestExpProtThrombolysInd Whether medical records suggest some kind of investigational thrombolytic protocol was used during provision of care Whether medical records suggest some kind of investigational thrombolytic protocol was used during provision of care Do the medical records suggest any type of investigational or experimental protocol for thrombolysis was used during provision of care Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one. If yes, explain the protocol used.
If investigational or experimental protocol was used there should be a signed IRB consent in the medical record.

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Single Pre-Defined Value Selected

C14401 Intra-arterial (IA) procedure initiated indicator IAProcInitInd Indicates whether an Intra-arterial (IA) procedure was initiated for participant/ subject at this hospital Indicates whether an Intra-arterial (IA) procedure was initiated for participant/ subject at this hospita Was an IA procedure initiated at this hospital Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one.

Endovascular procedures include mechanical thrombectomy and all uses of intra-arterial thrombolytic therapy. Mechanical thrombectomy may be used alone or in conjunction with intra-arterial thrombolytic therapy.

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry Adult;Pediatric Supplemental-Highly Recommended 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Single Pre-Defined Value Selected

C18927 IV tPA not started other text IVtPANotStartOTH The free-text field related to 'IV tPA not started reason' specifying other text. If NO Intravenous Tissue Plasminogen Activator (IV tPA) was initiated, documents reasons in the medical record for why no IV tPA was started for the participant/subject at your hospital. Were one or more of the following reasons for not administering IV thrombolytic therapy at this hospital explicitly documented by a physician, advance practice nurse, or physician assistant's notes in the medical record? The free-text field related to 'IV tPA not started other text' specifying other text. If NO Intravenous Tissue Plasminogen Activator initiated, documents reasons in the medical record for why no IV tPA was started Other, specify Alphanumeric

Choose all that apply.

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data 4000

Free-Form Entry

C14402 Intra-arterial (IA) procedure type IAProcTyp If intra-arterial (IA) procedure was initiated, describes the type of intra-arterial (IA) procedure performed on participant/ subject at this hospital If intra-arterial (IA) procedure was initiated, describes the type of intra-arterial (IA) procedure performed on participant/ subject at this hospital Type of IA procedure Pharmacological;Mechanical;Both Pharmacological;Mechanical;Both Alphanumeric

Choose one.

No references available Adult;Pediatric Supplemental-Highly Recommended 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Single Pre-Defined Value Selected

C58579 Investigational or experimental protocol for thrombolysis text InvestExpProtThrombolysTxt Free-text field to specify what type of investigational thrombolytic protocol was used during provision of care Free-text field to specify what type of investigational thrombolytic protocol was used during provision of care If YES, explain the protocol used Alphanumeric American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data 255

Free-Form Entry

C14403 Intra-arterial (IA) procedure groin puncture date and time IAProcGroinPuncDateTime Date (and time, if applicable and known) of groin puncture on the participant/ subject for the intra-arterial (IA) procedure Date (and time, if applicable and known) of groin puncture on the participant/ subject for the intra-arterial (IA) procedure Date and Time of groin puncture for IA procedure Date or Date & Time

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

No references available Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

C14404 Intra-arterial (IA) catheter-based reperfusion initiated date and time IACathBasdReperfsInitDateTime Date (and time, if applicable and known) of last intra-arterial (IA) catheter-based reperfusion initiated for the participant/ subject at this hospital or ED Date (and time, if applicable and known) of last intra-arterial (IA) catheter-based reperfusion initiated for the participant/ subject at this hospital or ED Date and Time IA catheter-based reperfusion initiated Date or Date & Time

The start time for endovascular reperfusion therapy should be either the date and time on the angio showing evidence of treatment, or the start time of the infusion or mechanical deployment if the angio time is not available.

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

C14405 Intervention mechanical or pharmacological end time IntrvntMechnPharmacEndTime The end time for mechanical, pharmacologic intervention for the participant/subject The end time for mechanical, pharmacologic intervention for the participant/subject Date and Time of last angiographic image or the end time for mechanical/pharmacologic intervention Date or Date & Time

If time of the last mechanical or pharmacological intervention not available, use the time on the last angiographic image.

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

No references available Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

C06005 Data collected date and time DataCollDateTime Date (and time, if applicable and known) the data were collected. This may be the date/time a particular examination or procedure was performed Date (and time, if applicable and known) the data were collected. This may be the date/time a particular examination or procedure was performe Date information collected Date or Date & Time

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

No references available Adult;Pediatric Supplemental 3.00 2013-07-24 21:00:23.88 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

C14406 Intra-arterial (IA) catheter-based reperfusion other hospital indicator IACathBasdReperfsnOthHospInd Indicates whether intra-arterial (IA) catheter-based reperfusion was initiated for the participant/subject at an outside hospital Indicates whether intra-arterial (IA) catheter-based reperfusion was initiated for the participant/subject at an outside hospital Was IA catheter-based reperfusion initiated at an outside hospital Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one.

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Single Pre-Defined Value Selected

C14396 IV tPA initiated status IVtPAInitiatStatus Indicates whether Intravenous Tissue Plasminogen Activator (IV tPA) was initiated for the participant/subject at your hospital Indicates whether Intravenous Tissue Plasminogen Activator (IV tPA) was initiated for the participant/subject at your hospital Was IV tPA initiated at this hospital Yes - within 0-3 hour window;Yes - within 3-4.5 hour window;No;Yes - beyond 4.5 hour using imaging selection Yes - within 0-3 hour window;Yes - within 3-4.5 hour window;No;Yes - beyond 4.5 hour using imaging selection Alphanumeric

This refers to IV tPA given at the FDA approved dose and within FDA approved guidelines.
Select Yes if IV tPA was given for acute ischemic stroke. Select No If IV tPA is not initiated at your hospital, even if there are documented contraindications or warnings to IV tPA. In the case that tPA is contraindicated, select No for IV tPA initiated at your hospital and select Yes for Documented Contraindications or Warnings for not initiating IV thrombolytic in either the 0-3 hour, 3-4.5 hour, or beyond 4.5 hour treatment window.

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry; The Joint Commission (TJC)<br /><br />Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, Ortega-Gutierrez S, McTaggart RA, Torbey MT, Kim-Tenser M, Leslie-Mazwi T, Sarraj A, Kasner SE, Ansari SA, Yeatts SD, Hamilton S, Mlynash M, Heit JJ, Zaharchuk G, Kim S, Carrozzella J, Palesch YY, Demchuk AM, Bammer R, Lavori PW, Broderick JP, Lansberg MG; DEFUSE 3 Investigators. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. N Engl J Med. 2018;378(8):708-718.<br /><br />Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA, Hassan AE, Millan M, Levy EI, Mitchell P, Chen M, English JD, Shah QA, Silver FL, Pereira VM, Mehta BP, Baxter BW, Abraham MG, Cardona P, Veznedaroglu E, Hellinger FR, Feng L, Kirmani JF, Lopes DK, Jankowitz BT, Frankel MR, Costalat V, Vora NA, Yoo AJ, Malik AM, Furlan AJ, Rubiera M, Aghaebrahim A, Olivot JM, Tekle WG, Shields R, Graves T, Lewis RJ, Smith WS, Liebeskind DS, Saver JL, Jovin TG; DAWN Trial Investigators. Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. N Engl J Med. 2018;378(1):11-21.<br /><br />Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, Bambakidis NC, Becker K, Biller J, Brown M, Demaerschalk BM, Hoh B, Jauch EC, Kidwell CS, Leslie-Mazwi TM, Ovbiagele B, Scott PA, Sheth KN, Southerland AM, Summers DV, Tirschwell DL; American Heart Association Stroke Council. 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. [published correction appears in Stroke. 2018 Mar;49(3):e138] [published correction appears in Stroke. 2018 Apr 18;:]. Stroke. 2018;49(3):e46-e110.<br /><br />Thomalla G, Simonsen CZ, Boutitie F, Andersen G, Berthezene Y, Cheng B, Cheripelli B, Cho TH, Fazekas F, Fiehler J, Ford I, Galinovic I, Gellissen S, Golsari A, Gregori J, G&uuml;nther M, Guibernau J, H?usler KG, Hennerici M, Kemmling A, Marstrand J, Modrau B, Neeb L, Perez de la Ossa N, Puig J, Ringleb P, Roy P, Scheel E, Schonewille W, Serena J, Sunaert S, Villringer K, Wouters A, Thijs V, Ebinger M, Endres M, Fiebach JB, Lemmens R, Muir KW, Nighoghossian N, Pedraza S, Gerloff C; WAKE-UP Investigators. MRI-Guided Thrombolysis for Stroke with Unknown Time of Onset. N Engl J Med. 2018;379(7):611-622. Adult;Pediatric Supplemental-Highly Recommended 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Single Pre-Defined Value Selected

C14407 Intra-sinus intervention indicator IntrasinIntrvntInd Indicates whether the participant/subject received any intra-sinus (i.e., for cerebral venous thrombosis) intervention Indicates whether the participant/subject received any intra-sinus (i.e., for cerebral venous thrombosis) intervention Was an intra-sinus intervention performed Yes;No;Unknown Yes;No;Unknown Alphanumeric

Choose one.
Relevant to venous sinus and their large draining veins

No references available Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Single Pre-Defined Value Selected

C14397 IV tPA initiated date and time IVtPAInitiatDateTime If Intravenous Tissue Plasminogen Activator (IV tPA) was initiated, indicates the date and time IV tPA was initiated at this hospital or ED (time of bolus administration) If Intravenous Tissue Plasminogen Activator (IV tPA) was initiated, indicates the date and time IV tPA was initiated at this hospital or ED (time of bolus administration) Date and Time tPA initiated Date or Date & Time

This refers to IV tPA given at the FDA approved dose and within FDA approved guidelines. If there are discrepancies in the documentation of bolus administration, the nursing documentation on the medication administration sheets should be treated as the most reliable source, followed by the stroke physician's documented time or ED note.
This data element applies only to patients for whom IV thrombolytic therapy was initiated at this hospital. Do not abstract this data element if IV thrombolytic therapy was initiated at another hospital and patient was subsequently transferred to this hospital.

Record the date/time according to the ISO 8601, the International Standard for the representation of dates and times (http://www.iso.org/iso/home.html). The date/time should be recorded to the level of granularity known (e.g., year, year and month, complete date plus hours and minutes, etc.).

American Heart/American Stroke Association. (2018). Get With The Guidelines (GWTG) Stroke Patient Management Tool Coding Instructions (&copy; 2018, American Heart/American Stroke Association). Available at: https://www.heart.org/-/media/files/professional/quality-improvement/get-with-the-guidelines/get-with-the-guidelines-stroke/stroke-fact-sheet_-final_ucm_501842.pdf?la=en; Paul Coverdell National Acute Stroke Registry; The Joint Commission (TJC) Adult;Pediatric Supplemental-Highly Recommended 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Free-Form Entry

C14408 Intra-sinus procedure type IntrasinProcedTyp If intra-sinus (i.e., for cerebral venous thrombosis) intervention was received, specifies the type of intra-sinus procedure performed on the participant/subject at this hospital If intra-sinus (i.e., for cerebral venous thrombosis) intervention was received, specifies the type of intra-sinus procedure performed on the participant/subject at this hospital Type of intra-sinus procedure Pharmacological;Mechanical;Both Pharmacological;Mechanical;Both Alphanumeric

Choose one.

No references available Adult;Pediatric Supplemental 3.00 2013-06-21 00:00:00.0 Thrombolytic/Reperfusion Therapies Drugs Treatment%2FIntervention Data

Single Pre-Defined Value Selected

CSV